Literature DB >> 8652423

Trichloroethanol is not a metabolite of alpha chloralose.

P Kintz1, C Jamey, P Mangin.   

Abstract

Head space capillary gas chromatography was used to detect alpha chloralose and its potent metabolite, trichloroethanol in clinical and forensic cases. Although alpha chloralose was identified in blood and urine in all cases, trichloroethanol was never detected. In a fatal case the alpha chloralose concentration in blood was 151.3 mg/l. It was concluded that trichloroethanol is not a metabolite of alpha chloralose.

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Year:  1996        PMID： 8652423     DOI： 10.1007/bf01369790

Source DB:  PubMed          Journal:  Int J Legal Med        ISSN： 0937-9827            Impact factor:   2.686


  5 in total

Review 1.  Pharmacology and toxicology of alpha chloralose: a review.

Authors:  P Lees
Journal:  Vet Rec       Date:  1972-09-30       Impact factor: 2.695

2.  The investigation and pattern of occurrence of animal poisoning resulting from the misuse of agricultural chemicals.

Authors:  P M Brown; P J Bunyan; P I Stanley
Journal:  J Forensic Sci Soc       Date:  1977-10

3.  Electrocerebral changes in acute alpha-chloralose poisoning: a case report.

Authors:  L Manzo; P Richelmi; A Crema
Journal:  Vet Hum Toxicol       Date:  1979-08

4.  [Toxicologic analysis of chloralose. Application to 3 cases of acute intoxication].

Authors:  G Gras; C Pellissier; F Fauran
Journal:  Eur J Toxicol Environ Hyg       Date:  1975 Nov-Dec

5.  The toxic effects of alpha-chloralose.

Authors:  H M Thomas; D Simpson; L F Prescott
Journal:  Hum Toxicol       Date:  1988-05
  5 in total
  3 in total

1.  The Knoevenagel-Doebner reaction on 1,2-O-(2,2,2-trichloroethylidene) derivatives of D-gluco- and D-manno-furanose.

Authors:  Gökhan Kök; Tamer Karayıldırım; Kadir Ay; Emriye Ay
Journal:  Molecules       Date:  2010-10-29       Impact factor: 4.411

2.  Alpha-chloralose poisoning in cats in three Nordic countries - the importance of secondary poisoning.

Authors:  Ulrika Windahl; Annica Tevell Åberg; Fedor Kryuchkov; Sandra Lundgren; Cecilia Tegner; Kristoffer Dreimanis; Sanna Koivisto; Outi Simola; Morten Sandvik; Aksel Bernhoft
Journal:  BMC Vet Res       Date:  2022-09-05       Impact factor: 2.792

3.  Development and Validation of a Quantitative UHPLC-MS-MS Method for the Determination of Alpha-Chloralose in Feline Blood and Application on Blood Samples Collected from Cats with Symptoms of Alpha-Chloralose Poisoning.

Authors:  Ulrika Windahl; Sandra Lundgren; Margareta Sprycha; Cecilia Tegner; Kristoffer Dreimanis; Annica Tevell Åberg
Journal:  J Anal Toxicol       Date:  2022-07-14       Impact factor: 3.220
  3 in total

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