Literature DB >> 8652099

A new analogue of nifurtimox.

I Caracelli1, F M Stamato, B Mester, M Paulino, H Cerecetto.   

Abstract

1-¿[(5-Nitro-2-furyl)methylene]amino¿-1,2,4-triazole, C7H5N5O3, is a new analogue of nifurtimox with activity against Tripanosoma cruzi. In the crystal structure, the molecule lies on a mirror plane and has an E-sZ conformation along the N = C-C moiety. The molecules are linked through C-H...O and C-H...N interactions.

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Year:  1996        PMID: 8652099     DOI: 10.1107/s0108270195015824

Source DB:  PubMed          Journal:  Acta Crystallogr C        ISSN: 0108-2701            Impact factor:   1.172


  1 in total

1.  A class of 5-nitro-2-furancarboxylamides with potent trypanocidal activity against Trypanosoma brucei in vitro.

Authors:  Linna Zhou; Gavin Stewart; Emeline Rideau; Nicholas J Westwood; Terry K Smith
Journal:  J Med Chem       Date:  2013-01-15       Impact factor: 7.446

  1 in total

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