Literature DB >> 8651928

Molecular cloning of human hyaluronan synthase.

N Itano1, K Kimata.   

Abstract

We report here the cDNA sequence of human hyaluronan synthase. The cDNA clone was isolated from a human fetal brain cDNA library by screening with a DNA probe generated from the coding sequence of murine hyaluronan synthase. It contains a 2107 bp cDNA insert which is composed of a 1629 bp open reading frame and a short segment of the 3'-untranslated region. Comparative analysis of the predicted coding region with the murine hyaluronan synthase sequence indicates 84.4% and 96.0% identity in nucleotide sequence and amino acid sequences, respectively. Northern analysis indicated that the gene was ubiquitously expressed in various human tissues.

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Year:  1996        PMID： 8651928     DOI： 10.1006/bbrc.1996.0827

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  29 in total

1.  Inhibition of hyaluronan degradation by dextran sulphate facilitates characterisation of hyaluronan synthesis: an in vitro and in vivo study.

Authors:  Lishanthi Udabage; Gary R Brownlee; Robert Stern; Tracey J Brown
Journal:  Glycoconj J       Date:  2004       Impact factor: 2.916

2.  Site-directed mutation of conserved cysteine residues does not inactivate the Streptococcus pyogenes hyaluronan synthase.

Authors:  C D Heldermon; V L Tlapak-Simmons; B A Baggenstoss; P H Weigel
Journal:  Glycobiology       Date:  2001-12       Impact factor: 4.313

3.  Genome-wide association study of suicide attempts in mood disorder patients.

Authors:  Roy H Perlis; Jie Huang; Shaun Purcell; Maurizio Fava; A John Rush; Patrick F Sullivan; Steven P Hamilton; Francis J McMahon; Thomas G Schulze; Thomas Schulze; James B Potash; Peter P Zandi; Virginia L Willour; Brenda W Penninx; Dorret I Boomsma; Nicole Vogelzangs; Christel M Middeldorp; Marcella Rietschel; Markus Nöthen; Sven Cichon; Hugh Gurling; Nick Bass; Andrew McQuillin; Marian Hamshere; Nick Craddock; Pamela Sklar; Jordan W Smoller
Journal:  Am J Psychiatry       Date:  2010-11-01       Impact factor: 18.112

4.  Hyaluronan production in human rheumatoid fibroblastic synovial lining cells is increased by interleukin 1 beta but inhibited by transforming growth factor beta 1.

Authors:  M Kawakami; K Suzuki; Y Matsuki; T Ishizuka; T Hidaka; T Konishi; M Matsumoto; K Kataharada; H Nakamura
Journal:  Ann Rheum Dis       Date:  1998-10       Impact factor: 19.103

5.  UDP-glucose pyrophosphorylase: up-regulation in hypertrophic cartilage and role in hyaluronan synthesis.

Authors:  C Magee; M Nurminskaya; T F Linsenmayer
Journal:  Biochem J       Date:  2001-12-15       Impact factor: 3.857

6.  Hyaluronan synthase expression in pleural malignant mesotheliomas.

Authors:  Naoki Kanomata; Tomoyuki Yokose; Tomoyuki Kamijo; Hiroyuki Yonou; Takahiro Hasebe; Naoki Itano; Koji Kimata; Atsushi Ochiai
Journal:  Virchows Arch       Date:  2005-02-25       Impact factor: 4.064

7.  Mycosporine-like amino acids stimulate hyaluronan secretion by up-regulating hyaluronan synthase 2 via activation of the p38/MSK1/CREB/c-Fos/AP-1 axis.

Authors:  Shuko Terazawa; Masahiko Nakano; Akio Yamamoto; Genji Imokawa
Journal:  J Biol Chem       Date:  2020-04-13       Impact factor: 5.157

Review 8.  Hyaluronan: genetic insights into the complex biology of a simple polysaccharide.

Authors:  John A McDonald; Todd D Camenisch
Journal:  Glycoconj J       Date:  2002 May-Jun       Impact factor: 2.916

9.  Chronic ultraviolet B irradiation causes loss of hyaluronic acid from mouse dermis because of down-regulation of hyaluronic acid synthases.

Authors:  Guang Dai; Till Freudenberger; Petra Zipper; Ariane Melchior; Susanne Grether-Beck; Berit Rabausch; Jens de Groot; Sören Twarock; Helmut Hanenberg; Bernhard Homey; Jean Krutmann; Julia Reifenberger; Jens W Fischer
Journal:  Am J Pathol       Date:  2007-11       Impact factor: 4.307

10.  Hyaluronan induces the selective accumulation of matrix- and cell-associated proteoglycans by mesangial cells.

Authors:  Sabine Kastner; Gareth J Thomas; Robert H Jenkins; Malcolm Davies; Robert Steadman
Journal:  Am J Pathol       Date:  2007-11-01       Impact factor: 4.307
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