Literature DB >> 8650260

Feedback regulation of map kinase signal pathways.

B Errede1, Q Y Ge.   

Abstract

Ste7 is a MEK (MAPK/ERK kinase) family member that functions in the pheromone induced mating response pathway of Saccharomyces cerevisiae. We analysed the catalytic competence and in vivo function of Ste7 variants that have alterations of stimulatory and feedback phosphorylation sites. These analyses led us to unanticipated insights into two separate feedback mechanisms that impede the output of the mating response MAPK activation pathway.

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Year:  1996        PMID： 8650260     DOI： 10.1098/rstb.1996.0010

Source DB:  PubMed          Journal:  Philos Trans R Soc Lond B Biol Sci        ISSN： 0962-8436            Impact factor:   6.237


  8 in total

Review 1.  Mitogen-activated protein kinases: specific messages from ubiquitous messengers.

Authors:  H J Schaeffer; M J Weber
Journal:  Mol Cell Biol       Date:  1999-04       Impact factor: 4.272

2.  Pheromone induction promotes Ste11 degradation through a MAPK feedback and ubiquitin-dependent mechanism.

Authors:  R K Esch; B Errede
Journal:  Proc Natl Acad Sci U S A       Date:  2002-06-20       Impact factor: 11.205

3.  Mathematical and computational analysis of adaptation via feedback inhibition in signal transduction pathways.

Authors:  Marcelo Behar; Nan Hao; Henrik G Dohlman; Timothy C Elston
Journal:  Biophys J       Date:  2007-05-18       Impact factor: 4.033

4.  Mutational analysis suggests that activation of the yeast pheromone response mitogen-activated protein kinase pathway involves conformational changes in the Ste5 scaffold protein.

Authors:  C Sette; C J Inouye; S L Stroschein; P J Iaquinta; J Thorner
Journal:  Mol Biol Cell       Date:  2000-11       Impact factor: 4.138

5.  Persistent activation by constitutive Ste7 promotes Kss1-mediated invasive growth but fails to support Fus3-dependent mating in yeast.

Authors:  Seth Maleri; Qingyuan Ge; Elizabeth A Hackett; Yuqi Wang; Henrik G Dohlman; Beverly Errede
Journal:  Mol Cell Biol       Date:  2004-10       Impact factor: 4.272

Review 6.  The role of adaptor protein Ste50-dependent regulation of the MAPKKK Ste11 in multiple signalling pathways of yeast.

Authors:  Massoud Ramezani-Rad
Journal:  Curr Genet       Date:  2003-03-11       Impact factor: 3.886

7.  Control of signaling in a MAP-kinase pathway by an RNA-binding protein.

Authors:  Susanne Prinz; Christine Aldridge; Stephen A Ramsey; R James Taylor; Timothy Galitski
Journal:  PLoS One       Date:  2007-02-28       Impact factor: 3.240

8.  Control of MAPK signaling specificity by a conserved residue in the MEK-binding domain of the yeast scaffold protein Ste5.

Authors:  Monica A Schwartz; Hiten D Madhani
Journal:  Curr Genet       Date:  2006-02-04       Impact factor: 2.695
  8 in total

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