| Literature DB >> 8648758 |
A Okumura1, K Machii, S Azuma, Y Toyoda, S Kyuwa.
Abstract
A persistently coronavirus-infected embryonic stem (ES) cell line A3/MHV was established by infecting an ES cell line, A3-1, with mouse hepatitis virus type-2. Although almost all A3/MHV cells were found infected, both A3/MHV and A3-1 cells expressed comparable levels of cell surface differentiation markers. In addition, A3/MHV cells retained the ability to form embryoid bodies. These results suggest that persistent coronavirus infection does not affect the differentiation of ES cells.Entities:
Mesh:
Year: 1996 PMID: 8648758 PMCID: PMC190306
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103