| Literature DB >> 8647656 |
E Allémann1, J Rousseau, N Brasseur, S V Kudrevich, K Lewis, J E van Lier.
Abstract
Hexadecafluoro zinc phthalocyanine (ZnPcF16), a second-generation sensitizer for the photodynamic therapy (PDT) of cancer, was formulated in polyethylene-glycol-coated poly(lactic acid) nanoparticles (PEG-coated PLA-NP) and tested in EMT-6 tumour-bearing mice for its photodynamic activity. The tumour response was compared to that induced by the same dye formulated as a Cremophor EL (CRM) emulsion. Formulation in the biodegradable NP improved PDT response of the tumour while providing prolonged tumour sensitivity towards PDT.Entities:
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Year: 1996 PMID: 8647656 DOI: 10.1002/(SICI)1097-0215(19960611)66:6<821::AID-IJC19>3.0.CO;2-5
Source DB: PubMed Journal: Int J Cancer ISSN: 0020-7136 Impact factor: 7.396