Literature DB >> 864757

Regression of bovine ocular carcinoma by treatment with a mycobacterial vaccine.

S J Kleinschuster, H J Rapp, D C Lueker, R A Kainer.   

Abstract

Hereford cows with naturally occurring ocular squamous cell carcinoma were treated by injection of BCG cell-wall vaccine into the tumor. Regression or arrest of disease was observed in 71% of treated animals. The disease progressed in all untreated animals and animals treated with improperly compounded vaccine. At autopsy, most animals with progressive disease had lymph node metastases.

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Year:  1977        PMID： 864757     DOI： 10.1093/jnci/58.6.1807

Source DB:  PubMed          Journal:  J Natl Cancer Inst        ISSN： 0027-8874            Impact factor:   13.506


  9 in total

1.  The immunopathological effects of intracolonic injection of Mycobacterium bovis BCG cell wall emulsions in guinea pigs.

Authors:  G L Cockerell; R W O'Donnell; M M Zgola
Journal:  Cancer Immunol Immunother       Date:  1982       Impact factor: 6.968

2.  Anchorage-dependent culture of line 10 guinea-pig hepatoma cells.

Authors:  S J Kleinschuster; H J Rapp; A V Johnston; K R Van Kampen; C C Muscoplat; J Bier
Journal:  Experientia       Date:  1980-10-15

3.  Successful tumour immunotherapy: possible role of antibodies to anti-inflammatory factors produced by neoplasms.

Authors:  M Nelson; D S Nelson; P B Spradbrow; V K Kuchroo; P A Jennings; G J Cianciolo; R Snyderman
Journal:  Clin Exp Immunol       Date:  1985-07       Impact factor: 4.330

4.  Immunotherapy of bovine ocular squamous cell carcinoma by repeated intralesional injections of live bacillus Calmette-Guérin (BCG) or BCG cell walls.

Authors:  V P Rutten; W R Klein; W A De Jong; W Misdorp; P A Steerenberg; W H De Jong; W Den Otter; E J Ruitenberg
Journal:  Cancer Immunol Immunother       Date:  1991       Impact factor: 6.968

5.  Local bacillus Calmette-Guérin therapy for bovine vulval papilloma and carcinoma.

Authors:  F W Hill; V P Rutten; M H Hoyer; W R Klein; J W Koten; P A Steerenberg; E J Ruitenberg; W Den Otter
Journal:  Cancer Immunol Immunother       Date:  1994-07       Impact factor: 6.968

6.  Clinico-pathological aspects of immunotherapy by intralesional injection of BCG cell walls or live BCG in bovine ocular squamous cell carcinoma.

Authors:  W Misdorp; W R Klein; E J Ruitenberg; G Hart; W H de Jong; P A Steerenberg
Journal:  Cancer Immunol Immunother       Date:  1985       Impact factor: 6.968

7.  Experimental screening of BCG preparations produced for cancer immunotherapy: safety and immunostimulating and antitumor activity of four consecutively produced batches.

Authors:  W H de Jong; P A Steerenberg; J G Kreeftenberg; R H Tiesjema; W Kruizinga; L M van Noorle Jansen; E J Ruitenberg
Journal:  Cancer Immunol Immunother       Date:  1984       Impact factor: 6.968

8.  Immunotherapy of guinea pigs with a transplanted hepatoma: comparison of intralesionally administered killed BCG cells and BCG cell walls.

Authors:  E Yarkoni; H J Rapp
Journal:  Infect Immun       Date:  1979-09       Impact factor: 3.441

9.  Influence of type of oil and surfactant concentration on the efficacy of emulsified Mycobacterium bovis BCG cell walls to induce tumor regression in guinea pigs.

Authors:  E Yarkoni; H J Rapp
Journal:  Infect Immun       Date:  1980-06       Impact factor: 3.441
  9 in total

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