Literature DB >> 864741

Spontaneous thymoma in an inbred strain of rat.

S M Hinsull, D Bellamy.   

Abstract

Thymomas that appear with high frequency in inbred WAB rats living into old age were examined. The spontaneous thymomas described were discrete, encapsulated bodies composed of lymphocytes and epithelial cells, with a predominance of lymphocytes. The rat neoplasms resembled the human thymomas, and their rate of incidence in older animals may suggest their use as models for the human condition.

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Mesh：

Year:  1977        PMID： 864741     DOI： 10.1093/jnci/58.6.1609

Source DB:  PubMed          Journal:  J Natl Cancer Inst        ISSN： 0027-8874            Impact factor:   13.506


  6 in total

1.  Comparative Incidences and Biological Outcomes for Thymoma in Various Rat Strains in National Toxicology Program Studies.

Authors:  Rebecca R Moore; Hiroaki Nagai; Rodney A Miller; Jerry F Hardisty; Neil Allison; Keith R Shockley; David E Malarkey
Journal:  Toxicol Pathol       Date:  2019-08-08       Impact factor: 1.902

2.  Thymoma originating from the cervical component of the thymus in a degu.

Authors:  Naka Okumura; Hirotaka Kondo; Shinichi Suzuki; Hisashi Shibuya
Journal:  J Vet Diagn Invest       Date:  2021-09-13       Impact factor: 1.569

3.  Oestrogen retards the development of spontaneous thymomas in BUF/Mna rats.

Authors:  T Ezaki; H Fujii; K Matsuno; R Kawatsu; M Kotani
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1992

4.  Mixed Thymoma in a Young Cynomolgus Monkey (Macaca fascicularis).

Authors:  Yuri Kotani; Junko Sato; Yumi Wako; Minoru Tsuchitani
Journal:  J Toxicol Pathol       Date:  2010-10-05       Impact factor: 1.628

5.  An intrinsic thymic epithelial abnormality is responsible for the spontaneous development of predominantly lymphocytic thymomas in BUF/Mna rats.

Authors:  O Taguchi; K Kontani; H Ikeda; M Matsuyama
Journal:  Jpn J Cancer Res       Date:  1992-11

6.  Nodular development of spontaneous epithelial thymoma in (ACI/NMs x BUF/Mna)F1 rats.

Authors:  M Matsuyama; T Matsuyama; T Ogiu; A Kojima
Journal:  Jpn J Cancer Res       Date:  1988-09
  6 in total

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