Literature DB >> 8645795

Hemophagocytosis: a complication of acute Q fever in a child.

M Hufnagel1, C Niemeyer, L B Zimmerhackl, T Tüchelmann, S Sauter, M Brandis.   

Abstract

We describe an 11-year-old boy with acute Q fever complicated by hemophagocytosis. In addition to pancytopenia, the boy presented with hyponatremia, hypofibrinogenemia, and changes in lipid metabolism. Examination of a bone marrow aspirate revealed striking hemophagocytosis. All of the pathological changes were caused by an activated macrophage system. We also discuss the possible role that pathogenetic mechanisms play in these changes.

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Year:  1995        PMID: 8645795     DOI: 10.1093/clinids/21.4.1029

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  6 in total

Review 1.  From Q Fever to Coxiella burnetii Infection: a Paradigm Change.

Authors:  Carole Eldin; Cléa Mélenotte; Oleg Mediannikov; Eric Ghigo; Matthieu Million; Sophie Edouard; Jean-Louis Mege; Max Maurin; Didier Raoult
Journal:  Clin Microbiol Rev       Date:  2017-01       Impact factor: 26.132

2.  Coxiella burnetii causing haemophagocytic syndrome: a rare complication of an unusual pathogen.

Authors:  P Harris; R Dixit; R Norton
Journal:  Infection       Date:  2011-06-29       Impact factor: 3.553

3.  Q fever during pregnancy: an emerging cause of prematurity and abortion.

Authors:  F Jover-Díaz; J Robert-Gates; L Andreu-Gimenez; J Merino-Sanchez
Journal:  Infect Dis Obstet Gynecol       Date:  2001

4.  Coxiella burnetii Infection With Severe Hyperferritinemia in an Asplenic Patient.

Authors:  Allison Paine; Tadashi Miya; Brandon J Webb
Journal:  Open Forum Infect Dis       Date:  2015-08-26       Impact factor: 3.835

Review 5.  Hemophagocytic lymphohistiocytosis: review of etiologies and management.

Authors:  Melissa R George
Journal:  J Blood Med       Date:  2014-06-12

6.  Clinical Features and Complications of Coxiella burnetii Infections From the French National Reference Center for Q Fever.

Authors:  Cléa Melenotte; Camélia Protopopescu; Matthieu Million; Sophie Edouard; M Patrizia Carrieri; Carole Eldin; Emmanouil Angelakis; Félix Djossou; Nathalie Bardin; Pierre-Edouard Fournier; Jean-Louis Mège; Didier Raoult
Journal:  JAMA Netw Open       Date:  2018-08-03
  6 in total

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