Literature DB >> 864495

Human chorionic gonadotropin produced by ectopic pinealoma in a girl with precocious puberty. Case report.

O Kubo, N Yamasaki, Y Kamijo, K Amano, K Kitamura, R Demura.   

Abstract

A case is reported in which a human chorionic gonadotropin (HCG-)-producing ectopic pinealoma was found in a 5-year-old girl with precocious puberty. Physical examination revealed abnormal breast enlargement. Endocrinological study disclosed a high plasma HCG concentration of 1192 ng/ml with a normal follicular stimulating hormone (FSH) level. The HCG content of the tumor was as high as 400 ng/mg of acetone dried tissue, but no FSH was detectable. This is the first reported case of precocious puberty associated with pineal tumor in a female.

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Year:  1977        PMID： 864495     DOI： 10.3171/jns.1977.47.1.0101

Source DB:  PubMed          Journal:  J Neurosurg        ISSN： 0022-3085            Impact factor:   5.115


  9 in total

1.  Diabetes insipidus and increased serum levels of leptin and lactate-dehydrogenase (LDH) in an adolescent boy with a primary intracranial germinoma. Case report and an endocrinological revaluation of literature.

Authors:  C Carella; M Rotondi; A Del Buono; A M Sinisi; M L Del Basso De Caro; C M Mone; L Vizioli; F Sorvillo; G Mazziotti; A Bellastella
Journal:  J Endocrinol Invest       Date:  1999 Jul-Aug       Impact factor: 4.256

2.  Clinical and hormonal studies in precocious puberty.

Authors:  S Khandekar; R J Dash
Journal:  Indian J Pediatr       Date:  1990 May-Jun       Impact factor: 1.967

3.  Neoplastic causes of abnormal puberty.

Authors:  Susanne Wendt; John Shelso; Karen Wright; Wayne Furman
Journal:  Pediatr Blood Cancer       Date:  2013-10-24       Impact factor: 3.167

4.  Pineal ganglioglioma with premature thelarche. Report of a case and review of the literature.

Authors:  Y L Chang; S Z Lin; Y H Chiang; M Y Liu; W H Lee
Journal:  Childs Nerv Syst       Date:  1996-02       Impact factor: 1.475

Review 5.  Prognostic factors and therapeutic problems of primary intracranial choriocarcinoma/germ-cell tumors with high levels of HCG.

Authors:  Jun Shinoda; Noboru Sakai; Hirohito Yano; Tatsuaki Hattori; Akio Ohkuma; Heima Sakaguchi
Journal:  J Neurooncol       Date:  2004-01       Impact factor: 4.130

6.  Intracranial mixed germ cell tumor with syncytiotrophoblastic giant cells and precocious puberty.

Authors:  A Aguzzi; C E Hedinger; P Kleihues; M G Yaşargil
Journal:  Acta Neuropathol       Date:  1988       Impact factor: 17.088

7.  Neurosurgical experience with tumours of the pineal region at Clinica Puerta de Hierro.

Authors:  J Vaquero; J Ramiro; R Martínez; G Bravo
Journal:  Acta Neurochir (Wien)       Date:  1992       Impact factor: 2.216

8.  Experimental and spontaneous pineal tumors: findings relating to endocrine and oncogenic factors and mechanisms.

Authors:  W B Quay
Journal:  J Neural Transm       Date:  1980       Impact factor: 3.575

9.  Coincidental Central Precocious Puberty and Wilms Tumor in a 5-Year-Old Girl.

Authors:  Laura Kasongo; Patricia Forget; Ramona Corina Nicolescu
Journal:  Case Rep Pediatr       Date:  2019-09-08
  9 in total

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