Literature DB >> 864329

An improved procedure for the synthesis of glycine and taurine conjugates of bile acids.

K Y Tserng, D L Hachey, P D Klein.   

Abstract

Glycine and taurine conjugates of 5beta-cholanic acids have been synthesized using improved procedures based on the peptide coupling reagent, N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline. The conjugates are obtained in chromatographically pure form in yields higher than 90%. The use of this procedure in the large scale preparation of cholyl[1,2-13C2]glycine is described.

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Year:  1977        PMID: 864329

Source DB:  PubMed          Journal:  J Lipid Res        ISSN: 0022-2275            Impact factor:   5.922


  22 in total

1.  Energetics by NMR: site-specific binding in a positively cooperative system.

Authors:  Gregory P Tochtrop; Klaus Richter; Changguo Tang; James J Toner; Douglas F Covey; David P Cistola
Journal:  Proc Natl Acad Sci U S A       Date:  2002-02-19       Impact factor: 11.205

2.  An improved synthesis of taurine- and glycine-conjugated bile acids.

Authors:  T Momose; T Tsubaki; T Iida; T Nambara
Journal:  Lipids       Date:  1997-07       Impact factor: 1.880

3.  Human liver steroid sulphotransferase sulphates bile acids.

Authors:  A Radominska; K A Comer; P Zimniak; J Falany; M Iscan; C N Falany
Journal:  Biochem J       Date:  1990-12-15       Impact factor: 3.857

4.  Mapping interactions between germinants and Clostridium difficile spores.

Authors:  Amber Howerton; Norma Ramirez; Ernesto Abel-Santos
Journal:  J Bacteriol       Date:  2010-10-22       Impact factor: 3.490

5.  A method for the simultaneous analysis of unconjugated and glycine-conjugated bile acids by capillary gas-liquid chromatography.

Authors:  T Iida; T Itoh; K Hagiwara; F C Chang; J Goto; T Nambara
Journal:  Lipids       Date:  1989-12       Impact factor: 1.880

6.  Structural requirements of bile acid transporters: C-3 and C-7 modifications of steroidal hydroxyl groups.

Authors:  Vidula Kolhatkar; James E Polli
Journal:  Eur J Pharm Sci       Date:  2012-03-03       Impact factor: 4.384

7.  Feedback regulation of bile-acid synthesis in the rat. Differing effects of taurocholate and tauroursocholate.

Authors:  S Shefer; L Nguyen; G Salen; A K Batta; D Brooker; F G Zaki; I Rani; G S Tint
Journal:  J Clin Invest       Date:  1990-04       Impact factor: 14.808

8.  Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2).

Authors:  P Oelkers; L C Kirby; J E Heubi; P A Dawson
Journal:  J Clin Invest       Date:  1997-04-15       Impact factor: 14.808

9.  Bile acids: LXI. Synthesis and properties of conjugates of 5α-bile acids.

Authors:  R Shaw; W H Elliott
Journal:  Lipids       Date:  1980-10       Impact factor: 1.880

10.  A study on the influence of bile acid chemical structure on dissolution of insoluble calcium salts: an in vitro study of the use of bile acid-phosphatidylcholine-cholesterol model bile solution.

Authors:  M Yoneda; N Tamasawa; K Takebe; I Makino
Journal:  Gastroenterol Jpn       Date:  1990-06
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