Literature DB >> 8642599

The C-terminal domain revealed in the structure of RNA polymerase II.

G D Meredith1, W H Chang, Y Li, D A Bushnell, S A Darst, R D Kornberg.   

Abstract

The location of the CTD in the structure of RNA polymerase II has been determined by electron crystallography at 16 A resolution. Difference maps between wild-type enzyme and that lacking the CTD, or with an antibody fragment bound in place of the CTD, disclose the site of attachment of the CTD to the polymerase. Appropriate display of the polymerase structure reveals the CTD as an element projecting from this site of attachment into solution. A low relative density and large volume of this element identify the CTD as a conformationally mobile region.

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Year:  1996        PMID: 8642599     DOI: 10.1006/jmbi.1996.0258

Source DB:  PubMed          Journal:  J Mol Biol        ISSN: 0022-2836            Impact factor:   5.469


  9 in total

1.  Topological localization of the carboxyl-terminal domain of RNA polymerase II in the initiation complex.

Authors:  M Douziech; D Forget; J Greenblatt; B Coulombe
Journal:  J Biol Chem       Date:  1999-07-09       Impact factor: 5.157

2.  A protein-protein interaction map of yeast RNA polymerase III.

Authors:  A Flores; J F Briand; O Gadal; J C Andrau; L Rubbi; V Van Mullem; C Boschiero; M Goussot; C Marck; C Carles; P Thuriaux; A Sentenac; M Werner
Journal:  Proc Natl Acad Sci U S A       Date:  1999-07-06       Impact factor: 11.205

Review 3.  DNA wrapping in transcription initiation by RNA polymerase II.

Authors:  B Coulombe
Journal:  Biochem Cell Biol       Date:  1999       Impact factor: 3.626

4.  Pin1 modulates RNA polymerase II activity during the transcription cycle.

Authors:  Yu-Xin Xu; James L Manley
Journal:  Genes Dev       Date:  2007-11-15       Impact factor: 11.361

5.  Structure of wild-type yeast RNA polymerase II and location of Rpb4 and Rpb7.

Authors:  G J Jensen; G Meredith; D A Bushnell; R D Kornberg
Journal:  EMBO J       Date:  1998-04-15       Impact factor: 11.598

6.  Structure and dynamics of the RNAPII CTDsome with Rtt103.

Authors:  Olga Jasnovidova; Tomas Klumpler; Karel Kubicek; Sergei Kalynych; Pavel Plevka; Richard Stefl
Journal:  Proc Natl Acad Sci U S A       Date:  2017-10-04       Impact factor: 11.205

7.  Architecture of an RNA polymerase II transcription pre-initiation complex.

Authors:  Kenji Murakami; Hans Elmlund; Nir Kalisman; David A Bushnell; Christopher M Adams; Maia Azubel; Dominika Elmlund; Yael Levi-Kalisman; Xin Liu; Brian J Gibbons; Michael Levitt; Roger D Kornberg
Journal:  Science       Date:  2013-09-26       Impact factor: 47.728

8.  Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain.

Authors:  Bede Portz; Feiyue Lu; Eric B Gibbs; Joshua E Mayfield; M Rachel Mehaffey; Yan Jessie Zhang; Jennifer S Brodbelt; Scott A Showalter; David S Gilmour
Journal:  Nat Commun       Date:  2017-05-12       Impact factor: 14.919

9.  Super Secondary Structure Consisting of a Polyproline II Helix and a β-Turn in Leucine Rich Repeats in Bacterial Type III Secretion System Effectors.

Authors:  Dashdavaa Batkhishig; Khurelbaatar Bilguun; Purevjav Enkhbayar; Hiroki Miyashita; Robert H Kretsinger; Norio Matsushima
Journal:  Protein J       Date:  2018-06       Impact factor: 2.371

  9 in total

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