Literature DB >> 864141

Absolute sterochemistry of the highly mutagenic 7,8-diol 9,10-epoxides derived from the potent carcinogen trans-7,8-dihydroxy-7,8-dihydrobenzol[a]pyrene.

H Yagi, H Akagi, D R Thakker, H D Mah, M Koreeda, D M Jerina.   

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Year:  1977        PMID： 864141     DOI： 10.1021/ja00449a066

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


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  9 in total

1.  Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.

Authors:  M K Buening; P G Wislocki; W Levin; H Yagi; D R Thakker; H Akagi; M Koreeda; D M Jerina; A H Conney
Journal:  Proc Natl Acad Sci U S A       Date:  1978-11       Impact factor: 11.205

2.  Chloride ions catalyze the formation of cis adducts in the binding of anti-benzo[a]pyrene diol epoxide to nucleic acids.

Authors:  A R Wolfe; J Yamamoto; T Meehan
Journal:  Proc Natl Acad Sci U S A       Date:  1994-02-15       Impact factor: 11.205

3.  Role of diaxial versus diequatorial hydroxyl groups in the tumorigenic activity of a benzo[a]pyrene bay-region diol epoxide.

Authors:  R L Chang; A W Wood; A H Conney; H Yagi; J M Sayer; D R Thakker; D M Jerina; W Levin
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

4.  Dose-dependent differences in the profile of mutations induced by an ultimate carcinogen from benzo[a]pyrene.

Authors:  S J Wei; R L Chang; C Q Wong; N Bhachech; X X Cui; E Hennig; H Yagi; J M Sayer; D M Jerina; B D Preston
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-15       Impact factor: 11.205

5.  Differences in mutagenicity and cytotoxicity of (+)- and (-)-benzo[a]pyrene 4,5-oxide: a synergistic interaction of enantiomers.

Authors:  R L Chang; A W Wood; W Levin; H D Mah; D R Thakker; D M Jerina; A H Conney
Journal:  Proc Natl Acad Sci U S A       Date:  1979-09       Impact factor: 11.205

6.  Crystal and molecular structure of a benzo[a]pyrene 7,8-diol 9,10-epoxide N2-deoxyguanosine adduct: absolute configuration and conformation.

Authors:  Isabella L Karle; Haruhiko Yagi; Jane M Sayer; Donald M Jerina
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-02       Impact factor: 11.205

7.  Mechanism of the inhibition of mutagenicity of a benzo[a]pyrene 7,8-diol 9,10-epoxide by riboflavin 5'-phosphate.

Authors:  A W Wood; J M Sayer; H L Newmark; H Yagi; D P Michaud; D M Jerina; A H Conney
Journal:  Proc Natl Acad Sci U S A       Date:  1982-09       Impact factor: 11.205

8.  Identification of the major adducts formed by reaction of benzo(a)pyrene diol epoxide with DNA in vitro.

Authors:  K M Straub; T Meehan; A L Burlingame; M Calvin
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

9.  Synthesis of 13C4-labelled oxidized metabolites of the carcinogenic polycyclic aromatic hydrocarbon benzo[a]pyrene.

Authors:  Anhui Wu; Daiwang Xu; Ding Lu; Trevor M Penning; Ian A Blair; Ronald G Harvey
Journal:  Tetrahedron       Date:  2012-09-01       Impact factor: 2.457
  9 in total

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