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Literature DB >> 8641314

Simultaneous human immunodeficiency virus and Hepatitis C infection following a needlestick injury.

J M Garcés¹, H Yazbeck, T Pi-Sunyer, J Gutiérrez-Cebollada, J L López-Colomés.

Abstract

Needlestick injuries to health professionals at the Hospital del Mar, Barcelona since 1987 have been prospectively studied; a total of 296 such accidents in 286 subjects have been registered. We report the first case to our knowledge of simultaneous human immunodeficiency virus (HIV) and hepatitis C (HCV) infection in a nurse who suffered a needlestick injury after a blood sampling. Forty-four days after the accident she had symptoms and laboratory findings of acute hepatitis. Subsequent laboratory tests showed elevation in the aminotransferases and antibodies against HIV. The seroconversion to HCV was not detected until 109 days after the injury. The precise sequence of clinical and biological events of this case of simultaneous HIV and HCV infection is reported.

Entities: Disease

Mesh：

Year: 1996 PMID： 8641314 DOI： 10.1007/bf01586195

Source DB: PubMed Journal: Eur J Clin Microbiol Infect Dis ISSN： 0934-9723 Impact factor: 3.267

12 in total

1. Hepatitis C in hospital employees with needlestick injuries.

Authors: K Kiyosawa; T Sodeyama; E Tanaka; Y Nakano; S Furuta; K Nishioka; R H Purcell; H J Alter
Journal: Ann Intern Med Date: 1991-09-01 Impact factor: 25.391

2. Failed prophylactic zidovudine after needlestick injury.

Authors: D F Looke; D I Grove
Journal: Lancet Date: 1990-05-26 Impact factor: 79.321

3. HIV seroconversion after occupational exposure despite early prophylactic zidovudine therapy.

Authors:
Journal: Lancet Date: 1993-04-24 Impact factor: 79.321

Review 4. Hepatitis C virus six years on.

Authors: C L van der Poel; H T Cuypers; H W Reesink
Journal: Lancet Date: 1994-11-26 Impact factor: 79.321

5. Risk of transmitting the human immunodeficiency virus, cytomegalovirus, and hepatitis B virus to health care workers exposed to patients with AIDS and AIDS-related conditions.

Authors: J L Gerberding; C E Bryant-LeBlanc; K Nelson; A R Moss; D Osmond; H F Chambers; J R Carlson; W L Drew; J A Levy; M A Sande
Journal: J Infect Dis Date: 1987-07 Impact factor: 5.226

6. Surveillance for occupationally acquired HIV infection--United States, 1981-1992.

Authors:
Journal: MMWR Morb Mortal Wkly Rep Date: 1992-10-30 Impact factor: 17.586

7. Surveillance of HIV infection and zidovudine use among health care workers after occupational exposure to HIV-infected blood. The CDC Cooperative Needlestick Surveillance Group.

Authors: J I Tokars; R Marcus; D H Culver; C A Schable; P S McKibben; C I Bandea; D M Bell
Journal: Ann Intern Med Date: 1993-06-15 Impact factor: 25.391

Review 2. Viral infections in workers in hospital and research laboratory settings: a comparative review of infection modes and respective biosafety aspects.

Authors: Pedro B S Pedrosa; Telma A O Cardoso
Journal: Int J Infect Dis Date: 2011-04-14 Impact factor: 3.623

2 in total

Simultaneous human immunodeficiency virus and Hepatitis C infection following a needlestick injury.

1. Hepatitis C in hospital employees with needlestick injuries.

2. Failed prophylactic zidovudine after needlestick injury.

3. HIV seroconversion after occupational exposure despite early prophylactic zidovudine therapy.

Review 4. Hepatitis C virus six years on.

5. Risk of transmitting the human immunodeficiency virus, cytomegalovirus, and hepatitis B virus to health care workers exposed to patients with AIDS and AIDS-related conditions.

6. Surveillance for occupationally acquired HIV infection--United States, 1981-1992.

7. Surveillance of HIV infection and zidovudine use among health care workers after occupational exposure to HIV-infected blood. The CDC Cooperative Needlestick Surveillance Group.

8. Prophylactic zidovudine after occupational exposure to the human immunodeficiency virus: an interim analysis.

9. Prevalence of hepatitis C antibodies in clinical health-care workers.

Review 10. Occupational infection with human immunodeficiency virus (HIV). Risks and risk reduction.

Review 1. Managing occupational risks for hepatitis C transmission in the health care setting.

Review 2. Viral infections in workers in hospital and research laboratory settings: a comparative review of infection modes and respective biosafety aspects.