| Literature DB >> 8636819 |
Abstract
Repeated aspirations (for a period of 36 to 55 days) of the exudate through an open perforation were performed in seven children with acute otitis media that did not respond to antimicrobial therapy. Penicillin-resistant organisms were present in all but one of the first two aspirates. Failure to respond to antimicrobial therapy was associated with the emergence of resistant anaerobic and aerobic bacteria in the third and fourth cultures. The infection was cured in all instances after administration of antimicrobial agents effective against these bacteria.Entities:
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Year: 1996 PMID: 8636819 DOI: 10.1016/s0022-3476(96)70397-9
Source DB: PubMed Journal: J Pediatr ISSN: 0022-3476 Impact factor: 4.406