| Literature DB >> 8636227 |
M Nagahama1, L Orci, M Ravazzola, M Amherdt, L Lacomis, P Tempst, J E Rothman, T H Söllner.
Abstract
We report the identification of a putative v-SNARE (GOS-28), localized primarily to transport vesicles at the terminal rims of Golgi stacks. In vitro, GOS-28, A Golgi SNARE of 28 kD, is efficiently packaged into Golgi-derived vesicles, which are most likely COPI coated. Antibodies directed against GOS-28 block its ability to bind alpha-SNAP, partially inhibit transport from the cis to the medial cisternae, and do not inhibit budding of COP-coated vesicles, but do accumulate docked uncoated vesicles.Entities:
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Year: 1996 PMID: 8636227 PMCID: PMC2120813 DOI: 10.1083/jcb.133.3.507
Source DB: PubMed Journal: J Cell Biol ISSN: 0021-9525 Impact factor: 10.539