Literature DB >> 8635759

Acute overdose of zolpidem.

C L Winek1, W W Wahba, J K Janssen, L Rozin, V Rafizadeh.   

Abstract

Zolpidem (Ambien) is an imidazopyridine hypnotic recently introduced in the USA. We report a case of a fatal overdose of Ambien. A 68-year-old female ingested at least 30 tablets of 10 mg Ambien (300 mg). She was found dead at home. Toxicological analyses revealed blood concentration of 4.1, 19.3 and 2.3 micrograms/ml of zolpidem, meprobamate and carisoprodol, respectively.

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Year:  1996        PMID： 8635759     DOI： 10.1016/0379-0738(95)01875-1

Source DB:  PubMed          Journal:  Forensic Sci Int        ISSN： 0379-0738            Impact factor:   2.395


  7 in total

1.  Acute zolpidem overdose leading to coma and respiratory failure.

Authors:  A Hamad; N Sharma
Journal:  Intensive Care Med       Date:  2001-07       Impact factor: 17.440

Review 2.  Zolpidem: an update of its pharmacology, therapeutic efficacy and tolerability in the treatment of insomnia.

Authors:  K J Holm; K L Goa
Journal:  Drugs       Date:  2000-04       Impact factor: 9.546

Review 3.  Hypnotic Medications and Suicide: Risk, Mechanisms, Mitigation, and the FDA.

Authors:  W Vaughn McCall; Ruth M Benca; Peter B Rosenquist; Mary Anne Riley; Laryssa McCloud; Jill C Newman; Doug Case; Meredith Rumble; Andrew D Krystal
Journal:  Am J Psychiatry       Date:  2016-09-09       Impact factor: 18.112

4.  [Intoxication with a tricyclic antidepressant].

Authors:  S G Sakka; F Kuethe; U Demme; E Hüttemann
Journal:  Anaesthesist       Date:  2007-06       Impact factor: 1.041

5.  Zolpidem : Forensic aspects for the toxicologist and pathologist.

Authors:  Timothy P Rohrig; Christine M Moore
Journal:  Forensic Sci Med Pathol       Date:  2005-06       Impact factor: 2.456

6.  Zolpidem-induced suicide attempt: a case report.

Authors:  Sameh Mortaz Hejri; Mehrdad Faizi; Mohammad Babaeian
Journal:  Daru       Date:  2013-12-20       Impact factor: 3.117

7.  Quantitation of zolpidem in biological fluids by electro-driven microextraction combined with HPLC-UV analysis.

Authors:  Saeid Yaripour; Ali Mohammadi; Isa Esfanjani; Roderick B Walker; Saeed Nojavan
Journal:  EXCLI J       Date:  2018-04-23       Impact factor: 4.068
  7 in total

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