The structure of a new phospholipid from the koilin-glandular layer of chicken gizzard.

A new phospholipid (Mr = 653; C32H64NO10P; [alpha]22D: - 24) was isolated from the keratinoidal layer of chicken gizzard. After acid hydrolysis the following products were identified: a C22-saturated aldehyde, sn-glycerol 3-phosphate, ethanolamine and D(-)-ribose. The substance is stable to alkali, it has saturated character, and after hydrolysis with CH3OH/HCI, yields only C22-dimethyl acetal. It contains a free NH2 group, and methylation produces 2,3,4-tri-O-methyl-D-ribose. The probable structure of the isolated phospholipid is proposed as 1,2-O-do-cosylidene-sn-glycero-3-phospho-(1 inch-ribosyl)-ethanolamine.