Literature DB >> 8629250

Preoperative MRI diagnosis of Lhermitte-Duclos disease: case report with associated enlarged vessel and syrinx.

L J Wolansky1, G P Malantic, R Heary, A H Maniker, H J Lee, L R Sharer, U J Patel.   

Abstract

BACKGROUND: The most common primary cerebellar tumor is hemangioblastoma, a lesion which is associated with magnetic resonance imaging (MR)-detectable vascularity in over 60%. Lhermitte-Duclos disease is an uncommon cause of a cerebellar mass that is not typically vascular.
METHODS: Computed tomography (CT), MRI with and without contrast, and magnetic resonance venography was performed in a patient with a cerebellar mass.
RESULTS: The cerebellar mass was noted to have a prominent vessel, as well as an associated syrinx. In spite of MRI-detectable vascularity, the striped appearance of the lesion was felt to be typical of Lhermitte-Duclos disease. At surgery, the mass was resected and the diagnosis of Lhermitte-Duclos disease was confirmed.
CONCLUSIONS: The diagnosis of Lhermitte-Duclos disease should be made when MRI shows a parallel linear "tiger-striped" lesion of the cerebellum. The presence of an enlarged vessel and/or syrinx should not deter one from making the preoperative diagnosis.

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Mesh:

Year:  1996        PMID: 8629250     DOI: 10.1016/0090-3019(95)00244-8

Source DB:  PubMed          Journal:  Surg Neurol        ISSN: 0090-3019


  5 in total

Review 1.  Dysplastic gangliocytoma (Lhermitte-Duclos disease) associated with Cowden disease: report of a case and review of the literature for the genetic relationship between the two diseases.

Authors:  J Murata; M Tada; Y Sawamura; K Mitsumori; H Abe; K Nagashima
Journal:  J Neurooncol       Date:  1999-01       Impact factor: 4.130

2.  Symptomatic syringomyelia occurring as a late complication of posterior fossa medulloblastoma removal in infancy in a boy also suffering from scaphocephaly.

Authors:  Yassine El Hassani; Karim Burkhardt; Jacqueline Delavellle; Maria-Isabel Vargas; Colette Boex; Benedict Rilliet
Journal:  Childs Nerv Syst       Date:  2009-08-07       Impact factor: 1.475

3.  Assessing a dysplastic cerebellar gangliocytoma (Lhermitte-Duclos disease) with 7T MR imaging.

Authors:  Christoph Moenninghoff; Oliver Kraff; Marc Schlamann; Mark E Ladd; Zaza Katsarava; Elke R Gizewski
Journal:  Korean J Radiol       Date:  2010-02-22       Impact factor: 3.500

4.  Advanced MR imaging in Lhermitte-Duclos disease: moving closer to pathology and pathophysiology.

Authors:  B Thomas; T Krishnamoorthy; V V Radhakrishnan; C Kesavadas
Journal:  Neuroradiology       Date:  2007-06-05       Impact factor: 2.804

5.  Neuroimaging abnormalities in patients with Cowden syndrome: Retrospective single-center study.

Authors:  Radhika Dhamija; Steven M Weindling; Alyx B Porter; Leland S Hu; Christopher P Wood; Joseph M Hoxworth
Journal:  Neurol Clin Pract       Date:  2018-06
  5 in total

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