Literature DB >> 862886

Interaction of new derivatives of daunorubicin and adriamycin with DNA.

E Arlandini, A Vigevani, F Arcamone.   

Abstract

The interaction of a number of new derivatives of the antitumour antibiotics daunorubicin and adriamycin with calf-thymus DNA has been studied by equilibrium dialysis and low-shear viscosimetry. The results are interpreted in terms of structure of the compounds, also by examining molecular stereomodels.

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Year:  1977        PMID： 862886

Source DB:  PubMed          Journal:  Farmaco Sci        ISSN： 0430-0920


  4 in total

Review 1.  Idarubicin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the chemotherapy of cancer.

Authors:  L M Hollingshead; D Faulds
Journal:  Drugs       Date:  1991-10       Impact factor: 9.546

2.  Anthracycline-binding induced DNA stiffening, bending and elongation; stereochemical implications from viscometric investigations.

Authors:  K E Reinert
Journal:  Nucleic Acids Res       Date:  1983-05-25       Impact factor: 16.971

3.  Human pharmacokinetics of the daunorubicin-DNA complex. An alternative view of the lysosomotropic theory.

Authors:  R Hulhoven; G Sokal; C Harvengt
Journal:  Cancer Chemother Pharmacol       Date:  1979       Impact factor: 3.333

4.  Synthesis, biological and biochemical properties of new anthracyclines modified in the aminosugar moiety.

Authors:  A Bargiotti; A M Casazza; G Cassinelli; A Di Marco; S Penco; G Pratesi; R Supino; A Zaccara; F Zunino; F Arcamone
Journal:  Cancer Chemother Pharmacol       Date:  1983       Impact factor: 3.333
  4 in total

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