Literature DB >> 862784

Phalloidin poisoning of isolated hepatocytes: inhibition of protein synthesis.

E Gravela, G Poli.   

Abstract

Phalloidin added to isolated hepatocytes inhibits amino acid incorporation into protein. Inhibition is very strong with 20 micrograms/ml phalloidin and occurs after a lag period of about 30 min. After this period, poisoned hepatocytes also show morphological changes in their plasma membrane.

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Year:  1977        PMID： 862784     DOI： 10.1007/bf01946523

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  8 in total

1.  Rapid proliferation of sublines of NCTC clone 929 (strain L) mouse cells in a simple chemically defined medium (MB 752/1).

Authors:  C WAYMOUTH
Journal:  J Natl Cancer Inst       Date:  1959-05       Impact factor: 13.506

2.  Albumin, fibrinogen and transferrin synthesis in isolated rat hepatocyte suspensions. A model for the study of plasma protein synthesis.

Authors:  K N Jeejeebhoy; J Ho; G R Greenberg; M J Phillips; A Bruce-Robertson; U Sodtke
Journal:  Biochem J       Date:  1975-01       Impact factor: 3.857

3.  Electron microscopy of isolated rat hepatocytes before and after treatment with phalloidin.

Authors:  E Weiss; I Sterz; M Frimmer; R Kroker
Journal:  Beitr Pathol       Date:  1973-12

4.  The role of extracellular K plus-concentration in phalloidin effects on isolated hepatocytes and perfused rat livers.

Authors:  M Frimmer; R Kroker
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1973       Impact factor: 3.000

5.  Toxic cyclopeptides of the toadstool Amanita phalloides and related species.

Authors:  M Frimmer
Journal:  Naunyn Schmiedebergs Arch Pharmakol       Date:  1971

6.  [Electron microscopic studies on the mouse and rat livers in acute phalloidin poisoning].

Authors:  F Miller; O Wieland
Journal:  Virchows Arch Pathol Anat Physiol Klin Med       Date:  1967

7.  Early polyribosomal and lysosomal changes in the liver of rats poisoned with Amanita phalloides or phalloidin.

Authors:  E Gravela; M F Zuretti; G Poli
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1975-09

8.  High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study.

Authors:  M N Berry; D S Friend
Journal:  J Cell Biol       Date:  1969-12       Impact factor: 10.539
  8 in total

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