PURPOSE: We determined whether cystic fibrosis patients are at increased risk for the development of urolithiasis. MATERIALS AND METHODS: Telephone interviews were conducted with 201 cystic fibrosis patients older than 15 years to identify those with a history of urolithiasis. Histories were confirmed by chart review, and only patients with urolithiasis documented by excretory urography, renal ultrasound or spontaneous passage of a stone were included. RESULTS: A total of 11 patients (5.5%) had documented urolithiasis, with 2 or more episodes in 7. Mean age at initial episode was 27.0 years (range 19 to 33). CONCLUSIONS: Cystic fibrosis patients may be at increased risk for urolithiasis compared to age-specific prevalence rates for stone disease in the general population.
PURPOSE: We determined whether cystic fibrosispatients are at increased risk for the development of urolithiasis. MATERIALS AND METHODS: Telephone interviews were conducted with 201 cystic fibrosispatients older than 15 years to identify those with a history of urolithiasis. Histories were confirmed by chart review, and only patients with urolithiasis documented by excretory urography, renal ultrasound or spontaneous passage of a stone were included. RESULTS: A total of 11 patients (5.5%) had documented urolithiasis, with 2 or more episodes in 7. Mean age at initial episode was 27.0 years (range 19 to 33). CONCLUSIONS:Cystic fibrosispatients may be at increased risk for urolithiasis compared to age-specific prevalence rates for stone disease in the general population.
Authors: Felix Knauf; Robert B Thomson; John F Heneghan; Zhirong Jiang; Adedotun Adebamiro; Claire L Thomson; Christina Barone; John R Asplin; Marie E Egan; Seth L Alper; Peter S Aronson Journal: J Am Soc Nephrol Date: 2016-06-16 Impact factor: 10.121