Literature DB >> 8627730

Predominant involvement of CD8+CD28- lymphocytes in human immunodeficiency virus-specific cytotoxic activity.

S Fiorentino1, M Dalod, D Olive, J G Guillet, E Gomard.   

Abstract

Distinct functional CD8+ T-cell populations have been observed during human immunodeficiency virus (HIV) infection. One of these functions is the inhibition of viral replication by a noncytotoxic mechanism, which was shown to be mediated by the CD8+CD28+ subpopulation. On the other hand, CD8+ T cells exert an HIV-specific cytotoxic activity. The present study shows that CD8+CD28- lymphocytes display this HIV-specific cytotoxic activity, which is detectable immediately after the cells are purified from peripheral blood. The CD28- population is also able to proliferate and to retain its cytotoxic activity after in vitro restimulation with autologous blast cells. Finally, HIV-specific cytotoxic T cells can be obtained in vitro from the CD8+CD28+ population.

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Year:  1996        PMID： 8627730      PMCID： PMC190033     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  29 in total

1.  CD28 interaction with B7 costimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes.

Authors:  M Azuma; M Cayabyab; D Buck; J H Phillips; L L Lanier
Journal:  J Exp Med       Date:  1992-02-01       Impact factor: 14.307

2.  Role of different lymphocyte subsets in human anti-viral T cell cultures.

Authors:  A Gomez; I Bourgault; E Gomard; F Picard; J P Levy
Journal:  Cell Immunol       Date:  1989-02       Impact factor: 4.868

3.  Suppression of simian immunodeficiency virus replication in vitro by CD8+ lymphocytes.

Authors:  M Kannagi; L V Chalifoux; C I Lord; N L Letvin
Journal:  J Immunol       Date:  1988-04-01       Impact factor: 5.422

4.  Different patterns of HIV-1-specific cytotoxic T-lymphocyte activity after primary infection.

Authors:  S Lamhamedi-Cherradi; B Culmann-Penciolelli; B Guy; T D Ly; C Goujard; J G Guillet; E Gomard
Journal:  AIDS       Date:  1995-05       Impact factor: 4.177

5.  Qualitative and quantitative analysis of human cytotoxic T-lymphocyte responses to HIV-1 proteins.

Authors:  S Lamhamedi-Cherradi; B Culmann-Penciolelli; B Guy; M P Kiény; F Dreyfus; A G Saimot; D Sereni; D Sicard; J P Lévy; E Gomard
Journal:  AIDS       Date:  1992-11       Impact factor: 4.177

6.  Alloantigen-specific cytotoxic and suppressor T lymphocytes are derived from phenotypically distinct precursors.

Authors:  N K Damle; N Mohagheghpour; J A Hansen; E G Engleman
Journal:  J Immunol       Date:  1983-11       Impact factor: 5.422

7.  HIV-specific cytotoxic T lymphocytes in seropositive individuals.

Authors:  B D Walker; S Chakrabarti; B Moss; T J Paradis; T Flynn; A G Durno; R S Blumberg; J C Kaplan; M S Hirsch; R T Schooley
Journal:  Nature       Date:  1987 Jul 23-29       Impact factor: 49.962

8.  Tumor rejection after direct costimulation of CD8+ T cells by B7-transfected melanoma cells.

Authors:  S E Townsend; J P Allison
Journal:  Science       Date:  1993-01-15       Impact factor: 47.728

9.  Induction of antigen-specific human cytotoxic T cells by Toxoplasma gondii.

Authors:  I A Khan; K A Smith; L H Kasper
Journal:  J Clin Invest       Date:  1990-06       Impact factor: 14.808

10.  Human immunodeficiency virus-specific cytotoxic responses of seropositive individuals: distinct types of effector cells mediate killing of targets expressing gag and env proteins.

Authors:  Y Riviere; F Tanneau-Salvadori; A Regnault; O Lopez; P Sansonetti; B Guy; M P Kieny; J J Fournel; L Montagnier
Journal:  J Virol       Date:  1989-05       Impact factor: 5.103
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  24 in total

1.  Weak anti-HIV CD8(+) T-cell effector activity in HIV primary infection.

Authors:  M Dalod; M Dupuis; J C Deschemin; C Goujard; C Deveau; L Meyer; N Ngo; C Rouzioux; J G Guillet; J F Delfraissy; M Sinet; A Venet
Journal:  J Clin Invest       Date:  1999-11       Impact factor: 14.808

2.  Expression of CD28 and CD38 by CD8+ T lymphocytes in HIV-1 infection correlates with markers of disease severity and changes towards normalization under treatment. The Swiss HIV Cohort Study.

Authors:  P Bürgisser; C Hammann; D Kaufmann; M Battegay; O T Rutschmann
Journal:  Clin Exp Immunol       Date:  1999-03       Impact factor: 4.330

3.  Human immunodeficiency virus type 1 induces apoptosis in CD4(+) but not in CD8(+) T cells in ex vivo-infected human lymphoid tissue.

Authors:  J C Grivel; N Malkevitch; L Margolis
Journal:  J Virol       Date:  2000-09       Impact factor: 5.103

4.  Mesenchymal stem cells control alloreactive CD8(+) CD28(-) T cells.

Authors:  A U Engela; C C Baan; N H R Litjens; M Franquesa; M G H Betjes; W Weimar; M J Hoogduijn
Journal:  Clin Exp Immunol       Date:  2013-12       Impact factor: 4.330

Review 5.  CD8+ CD28- and CD8+ CD57+ T cells and their role in health and disease.

Authors:  Marius Strioga; Vita Pasukoniene; Dainius Characiejus
Journal:  Immunology       Date:  2011-06-29       Impact factor: 7.397

6.  Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaques.

Authors:  T Matano; R Shibata; C Siemon; M Connors; H C Lane; M A Martin
Journal:  J Virol       Date:  1998-01       Impact factor: 5.103

7.  Analysis of CD28 and bcl-2 expression on peripheral blood and liver-infiltrating mononuclear cells in patients with autoimmune hepatitis.

Authors:  Kazutaka Kurokohchi; Keiji Arima; Tsutomu Masaki; Akiihiro Deguchi; Seiji Nakai; Asahiro Morishita; Hirohito Yoneyama; Tomohiro Ohgi; Masahiro Ono; Akira Yoshitake; Tsuyoshi Maeta; Yoshihiro Mori; Fumikazu Kohi; Mikio Nishioka; Shigeki Kuriyama
Journal:  J Clin Immunol       Date:  2006-06-16       Impact factor: 8.317

8.  Comparative analysis of cytotoxic T lymphocytes in lymph nodes and peripheral blood of simian immunodeficiency virus-infected rhesus monkeys.

Authors:  M J Kuroda; J E Schmitz; W A Charini; C E Nickerson; C I Lord; M A Forman; N L Letvin
Journal:  J Virol       Date:  1999-02       Impact factor: 5.103

9.  Correlates of immune activation marker changes in human immunodeficiency virus (HIV)-seropositive and high-risk HIV-seronegative women who use illicit drugs.

Authors:  Alan Landay; Lorie Benning; James Bremer; Barbara Weiser; Harold Burger; Marek Nowicki; Andrea Kovacs
Journal:  J Infect Dis       Date:  2003-07-01       Impact factor: 5.226

10.  CD8beta/CD28 expression defines functionally distinct populations of peripheral blood T lymphocytes.

Authors:  S Werwitzke; A Tiede; B E Drescher; R E Schmidt; T Witte
Journal:  Clin Exp Immunol       Date:  2003-09       Impact factor: 4.330
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