Literature DB >> 862763

Relation between stimulus intensity and neutrophil chemotactic response.

H U Keller, J H Wissler, M W Hess, H Cottier.   

Abstract

The effect of chemotactic peptides which lack chemokinetic activity has been investigated. The neutrophil response is proportional to the logarithm of the stimulus intensity, or alternatively a power function with an exponent of 0.3. Equal responses are obtained for equal ratios between the peptide concentration in the lower compartment and the threshold concentration. The significance of Weber-Fechner's law in leucocyte chemotaxis is discussed.

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Year:  1977        PMID： 862763     DOI： 10.1007/bf01922257

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  5 in total

1.  Chemistry and biology of the anaphylatoxin related serum peptide system. 3. Evaluation of leucotactic activity as a property of a new peptide system with classical anaphylatoxin and cocytotaxin as components.

Authors:  J H Wissler; V J Stecher; E Sorkin
Journal:  Eur J Immunol       Date:  1972-02       Impact factor: 5.532

2.  Chemistry and biology of the anaphylatoxin related serum peptide system. I. Purification, crystallization and properties of classical anaphylatoxin from rat serum.

Authors:  J H Wissler
Journal:  Eur J Immunol       Date:  1972-02       Impact factor: 5.532

3.  Studies on the regulation of the neutrophil chemotactic response using a rapid and reliable method for measuring random migration and chemotaxis of neutrophil granulocytes.

Authors:  H U Keller; H Gerber; M W Hess; H Cottier
Journal:  Agents Actions       Date:  1976-02

4.  Leukocyte locomotion and chemotaxis. New methods for evaluation, and demonstration of a cell-derived chemotactic factor.

Authors:  S H Zigmond; J G Hirsch
Journal:  J Exp Med       Date:  1973-02-01       Impact factor: 14.307

5.  The deactivation of rabbit neutrophils by chemotactic factor and the nature of the activatable esterase.

Authors:  P A Ward; E L Becker
Journal:  J Exp Med       Date:  1968-04-01       Impact factor: 14.307
  5 in total
  1 in total

1.  Chemotactic effects of the complement-derived peptides C3a, C3ai and C5a (classical anaphylatoxin) on rabbit and guinea-pig polymorphonuclear leukocytes.

Authors:  B Damerau; E Grünefeld; W Vogt
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1978-11       Impact factor: 3.000
  1 in total

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