| Literature DB >> 8627444 |
L M Oginni1, M Worsfold, O A Oyelami, C A Sharp, D E Powell, M W Davie.
Abstract
We studied 26 Nigerian children with active rickets (13 boys, 13 girls), aged 1 to 5 years, and compared results of biochemical studies with those of healthy control subjects. The plasma 1,25-dihydroxyvitamin D level was elevated (568 +/- 317 pmol/L) and the 25-hydroxyvitamin D level was (36 +/- 28 mol/L) in the children with rickets compared with the control subjects (369 +/- 134 nmol/L and 69 +/- 22 nmol/L, respectively). The results suggest that rickets in Nigeria is largely the result of calcium deficiency and that vitamin D deficiency and possibly end organ resistance may be contributory factors.Entities:
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Year: 1996 PMID: 8627444 DOI: 10.1016/s0022-3476(96)80137-5
Source DB: PubMed Journal: J Pediatr ISSN: 0022-3476 Impact factor: 4.406