Literature DB >> 8627262

Depletion of Mac1-positive macrophages protects DBA/2 mice from encephalomyocarditis virus-induced myocarditis and diabetes.

K Hirasawa1, S Tsutsui, M Takeda, M Mizutani, S Itagaki, K Doi.   

Abstract

DBA/2 mice treated with anti-Mac1 monoclonal antibody (MAb) failed to develop encephalomyocarditis virus (EMCV)-induced diabetes and myocarditis. Virus concentrations and the number of viral RNA-positive cells in the pancreas and heart were significantly reduced in mice treated with anti-Mac1 MAb. Mac1-positive macrophages seem to be involved in EMCV-induced disease and to affect the replication of EMCV in target organs.

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Year:  1996        PMID： 8627262     DOI： 10.1099/0022-1317-77-4-737

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  10 in total

1.  Role of Hck in the pathogenesis of encephalomyocarditis virus-induced diabetes in mice.

Authors:  K S Choi; H S Jun; H N Kim; H J Park; Y W Eom; H L Noh; H Kwon; H M Kim; J W Yoon
Journal:  J Virol       Date:  2001-02       Impact factor: 5.103

2.  A mechanism of immunoreceptor tyrosine-based activation motif (ITAM)-like sequences in the capsid protein VP2 in viral growth and pathogenesis of Coxsackievirus B3.

Authors:  Dae-Sun Kim; Jung-Hyun Park; Joo-Young Kim; Dokeun Kim; Jae-Hwan Nam
Journal:  Virus Genes       Date:  2011-10-26       Impact factor: 2.332

3.  Possible role of macrophage-derived soluble mediators in the pathogenesis of encephalomyocarditis virus-induced diabetes in mice.

Authors:  K Hirasawa; H S Jun; K Maeda; Y Kawaguchi; S Itagaki; T Mikami; H S Baek; K Doi; J W Yoon
Journal:  J Virol       Date:  1997-05       Impact factor: 5.103

4.  Prevention of encephalomyocarditis virus-induced diabetes in mice by inhibition of the tyrosine kinase signalling pathway and subsequent suppression of nitric oxide production in macrophages.

Authors:  K Hirasawa; H S Jun; H S Han; M L Zhang; M D Hollenberg; J W Yoon
Journal:  J Virol       Date:  1999-10       Impact factor: 5.103

5.  Role of nitric oxide in the pathogenesis of encephalomyocarditis virus-induced diabetes in mice.

Authors:  Young-Sun Lee; Na Li; Seungjin Shin; Hee-Sook Jun
Journal:  J Virol       Date:  2009-06-17       Impact factor: 5.103

Review 6.  Macrophage Expression of Inflammatory Genes in Response to EMCV Infection.

Authors:  Zachary R Shaheen; John A Corbett
Journal:  Biomolecules       Date:  2015-08-18

7.  The immunoproteasome-specific inhibitor ONX 0914 reverses susceptibility to acute viral myocarditis.

Authors:  Nadine Althof; Carl Christoph Goetzke; Meike Kespohl; Karolin Voss; Arnd Heuser; Sandra Pinkert; Ziya Kaya; Karin Klingel; Antje Beling
Journal:  EMBO Mol Med       Date:  2018-02       Impact factor: 12.137

8.  Silencing MicroRNA-155 Attenuates Cardiac Injury and Dysfunction in Viral Myocarditis via Promotion of M2 Phenotype Polarization of Macrophages.

Authors:  Yingying Zhang; Mengying Zhang; Xueqin Li; Zongsheng Tang; Xiangmin Wang; Min Zhong; Qifeng Suo; Yao Zhang; Kun Lv
Journal:  Sci Rep       Date:  2016-03-02       Impact factor: 4.379

9.  Long non-coding RNA AK085865 ablation confers susceptibility to viral myocarditis by regulating macrophage polarization.

Authors:  Yingying Zhang; Xueqin Li; Xiang Kong; Mengying Zhang; Deguo Wang; Yinhua Liu; Kun Lv
Journal:  J Cell Mol Med       Date:  2020-03-27       Impact factor: 5.310

Review 10.  Viruses in the Heart: Direct and Indirect Routes to Myocarditis and Heart Failure.

Authors:  Colton R Martens; Federica Accornero
Journal:  Viruses       Date:  2021-09-24       Impact factor: 5.048
  10 in total

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