Literature DB >> 8625281

Apoptosis amd metastasis: a superior resistance of metastatic cancer cells to programmed cell death.

G V Glinsky1, V V Glinsky.   

Abstract

We studied the response to different external signals leading to apoptosis of several poorly and highly metastatic cell lines employing a murine B16 melanoma experimental metastasis model. We found that highly metastatic cells exhibit a superior survival ability and resistance to apoptosis compared to poorly metastatic cells which would give the former an obvious selective growth advantage during tumor progression. Our results indicate that there is a genetic link between aggressive metastatic phenotype and resistance to apoptosis.

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Year:  1996        PMID： 8625281     DOI： 10.1016/0304-3835(96)04112-2

Source DB:  PubMed          Journal:  Cancer Lett        ISSN： 0304-3835            Impact factor:   8.679


  29 in total

1.  Resistance to apoptosis induced by microenvironmental stresses is correlated with metastatic potential in Lewis lung carcinoma.

Authors:  M Takasu; Y Tada; J O Wang; M Tagawa; K Takenaga
Journal:  Clin Exp Metastasis       Date:  1999-07       Impact factor: 5.150

2.  Alternatively spliced products CC3 and TC3 have opposing effects on apoptosis.

Authors:  S Whitman; X Wang; R Shalaby; E Shtivelman
Journal:  Mol Cell Biol       Date:  2000-01       Impact factor: 4.272

3.  The effects of three-dimensional cell culture on single myoblasts.

Authors:  Michele L Marquette; Diane Byerly; Marguerite Sognier
Journal:  In Vitro Cell Dev Biol Anim       Date:  2008-02-01       Impact factor: 2.416

4.  Caspase-3 expression in metastatic lymph nodes of esophageal squamous cell carcinoma is prognostic of survival.

Authors:  Xiu-Shen Wang; Kong-Jia Luo; Amos Ela Bella; Shan-Shan Bu; Jing Wen; Shui-Shen Zhang; Yi Hu
Journal:  World J Gastroenterol       Date:  2014-04-21       Impact factor: 5.742

5.  In vitro antimetastatic effect of Changweiqing through antiinvasion of hypoxic colorectal carcinoma LoVo cells.

Authors:  Jing Li; Zhong-Ze Fan; Jue Sun; Jian-Hua Xu
Journal:  Chin J Integr Med       Date:  2011-07-03       Impact factor: 1.978

6.  Nitric oxide mediates cell aggregation and mesenchymal to epithelial transition in anoikis-resistant lung cancer cells.

Authors:  Phattrakorn Powan; Pithi Chanvorachote
Journal:  Mol Cell Biochem       Date:  2014-04-27       Impact factor: 3.396

Review 7.  Adhesion molecules and chemokines: the navigation system for circulating tumor (stem) cells to metastasize in an organ-specific manner.

Authors:  Thomas Dittmar; Christoph Heyder; Eva Gloria-Maercker; Wolfgang Hatzmann; Kurt S Zänker
Journal:  Clin Exp Metastasis       Date:  2007-09-08       Impact factor: 5.150

8.  Malignancy-associated regions of transcriptional activation: gene expression profiling identifies common chromosomal regions of a recurrent transcriptional activation in human prostate, breast, ovarian, and colon cancers.

Authors:  Gennadi V Glinsky; Anja Krones-Herzig; Anna B Glinskii
Journal:  Neoplasia       Date:  2003 May-Jun       Impact factor: 5.715

9.  Microfabricated electrospun collagen membranes for 3-D cancer models and drug screening applications.

Authors:  Olga Hartman; Chu Zhang; Elizabeth L Adams; Mary C Farach-Carson; Nicholas J Petrelli; Bruce D Chase; John F Rabolt
Journal:  Biomacromolecules       Date:  2009-08-10       Impact factor: 6.988

10.  mtDNA G10398A variant in African-American women with breast cancer provides resistance to apoptosis and promotes metastasis in mice.

Authors:  Mariola Kulawiec; Kjerstin M Owens; Keshav K Singh
Journal:  J Hum Genet       Date:  2009-09-18       Impact factor: 3.172
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