Literature DB >> 8623747

Acetylcholine-induced prolongation of the QT interval in idiopathic long QT syndrome.

Y Aizawa1, T Washizuka, Y Igarashi, H Kitazawa, M Chinushi, A Abe, A Shibata.   

Abstract

Intracoronary acetylcholine prolonged the QT interval in 5 patients with congenital long QT syndrome but not in subjects with normal QT intervals. Prolongation was not due to bradycardia or adrenergic drive, and atropine was suggested to attenuate the response.

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Year:  1996        PMID: 8623747     DOI: 10.1016/s0002-9149(97)89189-8

Source DB:  PubMed          Journal:  Am J Cardiol        ISSN: 0002-9149            Impact factor:   2.778


  2 in total

1.  Relation between bradycardia dependent long QT syndrome and QT prolongation by disopyramide in humans.

Authors:  H Furushima; S Niwano; M Chinushi; K Ohhira; A Abe; Y Aizawa
Journal:  Heart       Date:  1998-01       Impact factor: 5.994

2.  Importance of vagally mediated bradycardia for the induction of torsade de pointes in an in vivo model.

Authors:  A Farkas; J Dempster; S J Coker
Journal:  Br J Pharmacol       Date:  2008-04-21       Impact factor: 8.739

  2 in total

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