| Literature DB >> 8621349 |
S Stevens-Miles1, M A Goetz, G F Bills, R A Giacobbe, J S Tkacz, R S Chang, M Mojena, I Martin, M T Diez, F Pelaez, O D Hensens, T Jones, R W Burg, Y L Kong, L Huang.
Abstract
Cytosporin A, B and C, three antagonists of [125I]-angiotensin II binding to rat adrenal glands were discovered in fermentations of an endophytic Cytospora sp. during routine screening using semi-automated procedures. The most potent of these displayed an IC50 of 1.5-3 microM and was specific for angiotensin II AT2.Entities:
Mesh：
Substances：
Year: 1996 PMID： 8621349 DOI： 10.7164/antibiotics.49.119
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649