Literature DB >> 862130

Metabolism of benzo[a]pyrene. VI. Stereoselective metabolism of benzo[a]pyrene and benzo[a]pyrene 7,8-dihydrodiol to diol epoxides.

D R Thakker, H Yagi, H Akagi, M Koreeda, A H Lu, W Levin, A W Wood, A H Conney, D M Jerina.   

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Year:  1977        PMID： 862130     DOI： 10.1016/0009-2797(77)90108-9

Source DB:  PubMed          Journal:  Chem Biol Interact        ISSN： 0009-2797            Impact factor:   5.192


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  17 in total

Review 1.  Metabolism and activation of chemical carcinogens.

Authors:  E K Weisburger
Journal:  Mol Cell Biochem       Date:  1980-09-15       Impact factor: 3.396

2.  Prenatal induction of benzo(a)pyrene hydroxylases in mice.

Authors:  D Neubert; S Tapken
Journal:  Arch Toxicol       Date:  1988       Impact factor: 5.153

3.  Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.

Authors:  M K Buening; P G Wislocki; W Levin; H Yagi; D R Thakker; H Akagi; M Koreeda; D M Jerina; A H Conney
Journal:  Proc Natl Acad Sci U S A       Date:  1978-11       Impact factor: 11.205

4.  The effect of the bay-region 12-methyl group on the stereoselective metabolism at the K-region of 7,12-dimethylbenz[a]anthracene by rat liver microsomes.

Authors:  S K Yang; P P Fu
Journal:  Biochem J       Date:  1984-11-01       Impact factor: 3.857

5.  Mutagenicity and tumorigenicity of the four enantiopure bay-region 3,4-diol-1,2-epoxide isomers of dibenz[a,h]anthracene.

Authors:  Richard L Chang; Alexander W Wood; Mou Tuan Huang; Jian Guo Xie; Xiao Xing Cui; Kenneth R Reuhl; D R Boyd; Yong Lin; Weichung Joe Shih; Suresh K Balani; Haruhiko Yagi; Donald M Jerina; Allan H Conney
Journal:  Carcinogenesis       Date:  2013-05-13       Impact factor: 4.944

6.  Mutagenicity and cytotoxicity of benz[alpha]anthracene diol epoxides and tetrahydro-epoxides: exceptional activity of the bay region 1,2-epoxides.

Authors:  A W Wood; R L Chang; W Levin; R E Lehr; M Schaefer-Ridder; J M Karle; D M Jerina; A H Conney
Journal:  Proc Natl Acad Sci U S A       Date:  1977-07       Impact factor: 11.205

7.  Crystal and molecular structure of a benzo[a]pyrene 7,8-diol 9,10-epoxide N2-deoxyguanosine adduct: absolute configuration and conformation.

Authors:  Isabella L Karle; Haruhiko Yagi; Jane M Sayer; Donald M Jerina
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-02       Impact factor: 11.205

8.  Mechanism of the inhibition of mutagenicity of a benzo[a]pyrene 7,8-diol 9,10-epoxide by riboflavin 5'-phosphate.

Authors:  A W Wood; J M Sayer; H L Newmark; H Yagi; D P Michaud; D M Jerina; A H Conney
Journal:  Proc Natl Acad Sci U S A       Date:  1982-09       Impact factor: 11.205

9.  Detection of benzo[a]pyrene diol epoxide-DNA adducts in human placenta.

Authors:  D K Manchester; A Weston; J S Choi; G E Trivers; P V Fennessey; E Quintana; P B Farmer; D L Mann; C C Harris
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

10.  Regio- and stereoselectivity of various forms of purified cytochrome P-450 in the metabolism of benzo[a]pyrene and (-) trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene as shown by product formation and binding to DNA.

Authors:  J Deutsch; J C Leutz; S K Yang; H V Gelboin; Y L Chiang; K P Vatsis; M J Coon
Journal:  Proc Natl Acad Sci U S A       Date:  1978-07       Impact factor: 11.205
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