| Literature DB >> 8619598 |
A L Walsh1, M D Smith, V Wuthiekanun, N J White.
Abstract
The postantibiotic effects (PAEs) OF 16 antibiotics or antibiotic combinations currently used against Burkholderia (Pseudomonas) pseudomallei were determined. The beta-lactams had zero PAEs, while the carbapenems and ciprofloxacin induced median PAEs of 1 and 5 h, respectively. These results emphasize the need to maintain antibiotic levels above inhibitory concentrations in blood throughout the dosing interval in cases of severe melioidosis.Entities:
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Year: 1995 PMID: 8619598 PMCID: PMC162945 DOI: 10.1128/AAC.39.10.2356
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191