Literature DB >> 8617928

A human killer inhibitory receptor specific for HLA-A1,2.

C Döhring1, D Scheidegger, J Samaridis, M Cella, M Colonna.   

Abstract

Killer inhibitory receptors (KIRs) are transmembrane glycoproteins, expressed on NK cells and a small subset of T cells, that inhibit cell-mediated cytotoxicity upon binding to polymorphic MHC class I determinants on target cells. Although human KIRs specific for HLA-C and HLA-B molecules have been characterized, none have been shown to interact with HLA-A. Here we demonstrate that a member of the KIR cDNA family, designated NKAT4, encodes a 70-kDa receptor specific for HLA-A3.

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Year:  1996        PMID: 8617928

Source DB:  PubMed          Journal:  J Immunol        ISSN: 0022-1767            Impact factor:   5.422


  76 in total

1.  Alloreactivity and association of human natural killer cells with the major histocompatibility complex.

Authors:  E Mavoungou; A Sall; V Poaty-Mavoungou; F S Toure; P Yaba; A Delicat; J Lansoud-Soukate
Journal:  Clin Diagn Lab Immunol       Date:  1999-03

2.  Degranulation of natural killer cells following interaction with HIV-1-infected cells is hindered by downmodulation of NTB-A by Vpu.

Authors:  Ankur H Shah; Bharatwaj Sowrirajan; Zachary B Davis; Jeffrey P Ward; Edward M Campbell; Vicente Planelles; Edward Barker
Journal:  Cell Host Microbe       Date:  2010-11-18       Impact factor: 21.023

3.  Mutation at positively selected positions in the binding site for HLA-C shows that KIR2DL1 is a more refined but less adaptable NK cell receptor than KIR2DL3.

Authors:  Hugo G Hilton; Luca Vago; Anastazia M Older Aguilar; Achim K Moesta; Thorsten Graef; Laurent Abi-Rached; Paul J Norman; Lisbeth A Guethlein; Katharina Fleischhauer; Peter Parham
Journal:  J Immunol       Date:  2012-07-06       Impact factor: 5.422

4.  Inhibitory receptors sensing HLA-G1 molecules in pregnancy: decidua-associated natural killer cells express LIR-1 and CD94/NKG2A and acquire p49, an HLA-G1-specific receptor.

Authors:  M Ponte; C Cantoni; R Biassoni; A Tradori-Cappai; G Bentivoglio; C Vitale; S Bertone; A Moretta; L Moretta; M C Mingari
Journal:  Proc Natl Acad Sci U S A       Date:  1999-05-11       Impact factor: 11.205

Review 5.  Human-specific evolution of killer cell immunoglobulin-like receptor recognition of major histocompatibility complex class I molecules.

Authors:  Peter Parham; Paul J Norman; Laurent Abi-Rached; Lisbeth A Guethlein
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2012-03-19       Impact factor: 6.237

6.  Presence of more activating KIR genes is associated with Hashimoto's thyroiditis.

Authors:  Elham Ashouri; Mohammad Hossein Dabbaghmanesh; Gholamhossein Ranjbar Omrani
Journal:  Endocrine       Date:  2013-10-31       Impact factor: 3.633

7.  Regulation of T cell lymphokine production by killer cell inhibitory receptor recognition of self HLA class I alleles.

Authors:  A D'Andrea; C Chang; J H Phillips; L L Lanier
Journal:  J Exp Med       Date:  1996-08-01       Impact factor: 14.307

8.  Alternatively spliced forms of human killer inhibitory receptors.

Authors:  C Döhring; J Samaridis; M Colonna
Journal:  Immunogenetics       Date:  1996       Impact factor: 2.846

9.  Different Selected Mechanisms Attenuated the Inhibitory Interaction of KIR2DL1 with C2+ HLA-C in Two Indigenous Human Populations in Southern Africa.

Authors:  Neda Nemat-Gorgani; Hugo G Hilton; Brenna M Henn; Meng Lin; Christopher R Gignoux; Justin W Myrick; Cedric J Werely; Julie M Granka; Marlo Möller; Eileen G Hoal; Makoto Yawata; Nobuyo Yawata; Lies Boelen; Becca Asquith; Peter Parham; Paul J Norman
Journal:  J Immunol       Date:  2018-03-16       Impact factor: 5.422

10.  Differential binding to HLA-C of p50-activating and p58-inhibitory natural killer cell receptors.

Authors:  M Valés-Gómez; H T Reyburn; R A Erskine; J Strominger
Journal:  Proc Natl Acad Sci U S A       Date:  1998-11-24       Impact factor: 11.205

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