Literature DB >> 8617181

Gabapentin associated with aggressive behavior in pediatric patients with seizures.

K B Tallian1, M C Nahata, W Lo, C Y Tsao.   

Abstract

Gabapentin (GBP) is a new antiepileptic drug (AED) approved for adjunctive treatment of complex partial seizures with or without seizures secondarily generalization in adults. We report 2 children who received GBP for intractable seizures and who developed intolerable aggressive behavior requiring dose reduction or drug discontinuation. Behavioral changes should be recognized as a possible side effect of GBP, especially in mentally retarded children.

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Year:  1996        PMID: 8617181     DOI: 10.1111/j.1528-1157.1996.tb00598.x

Source DB:  PubMed          Journal:  Epilepsia        ISSN: 0013-9580            Impact factor:   5.864


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