| Literature DB >> 8616018 |
T Witte1, F M Bode, M Hammer, H Deicher, R E Schmidt.
Abstract
A patient with Evans' syndrome is described who developed intermittently an immunocytopenia consisting of autoimmune neutropenia and natural killer (NK) cell deficiency. During this time an autoantibody binding to a 58 kD antigen expressed on granulocytes, activated NK cells and Epstein-Barr virus (EBV) transformed B cells was present. Incubation of activated NK cells and NK cell clones with the autoantibody leads to a significant inhibition of NK activity. Therefore the autoantibody may detect a functionally important activation molecule.Entities:
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Year: 1996 PMID： 8616018 DOI： 10.1046/j.1365-2141.1996.00369.x
Source DB: PubMed Journal: Br J Haematol ISSN： 0007-1048 Impact factor: 6.998