Literature DB >> 8614803

Cerebellum implicated in sensory acquisition and discrimination rather than motor control.

J H Gao1, L M Parsons, J M Bower, J Xiong, J Li, P T Fox.   

Abstract

Recent evidence that the cerebellum is involved in perception and cognition challenges the prevailing view that its primary function is fine motor control. A new alternative hypothesis is that the lateral cerebellum is not activated by the control of movement per se, but is strongly engaged during the acquisition and discrimination of sensory information. Magnetic resonance imaging of the lateral cerebellar output (dentate) nucleus during passive and active sensory tasks confirmed this hypothesis. These findings suggest that the lateral cerebellum may be active during motor, perceptual, and cognitive performances specifically because of the requirement to process sensory data.

Mesh:

Year:  1996        PMID: 8614803     DOI: 10.1126/science.272.5261.545

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  158 in total

1.  The cerebellum's role in reading: a functional MR imaging study.

Authors:  R K Fulbright; A R Jenner; W E Mencl; K R Pugh; B A Shaywitz; S E Shaywitz; S J Frost; P Skudlarski; R T Constable; C M Lacadie; K E Marchione; J C Gore
Journal:  AJNR Am J Neuroradiol       Date:  1999 Nov-Dec       Impact factor: 3.825

Review 2.  Exploring the role of the cerebellum in sensory anticipation and timing: commentary on Tesche and Karhu.

Authors:  R Ivry
Journal:  Hum Brain Mapp       Date:  2000-03       Impact factor: 5.038

3.  Brain activation in the processing of Chinese characters and words: a functional MRI study.

Authors:  L H Tan; J A Spinks; J H Gao; H L Liu; C A Perfetti; J Xiong; K A Stofer; Y Pu; Y Liu; P T Fox
Journal:  Hum Brain Mapp       Date:  2000-05       Impact factor: 5.038

4.  Neuroimaging evidence implicating cerebellum in support of sensory/cognitive processes associated with thirst.

Authors:  L M Parsons; D Denton; G Egan; M McKinley; R Shade; J Lancaster; P T Fox
Journal:  Proc Natl Acad Sci U S A       Date:  2000-02-29       Impact factor: 11.205

5.  Neuroimaging evidence implicating cerebellum in the experience of hypercapnia and hunger for air.

Authors:  L M Parsons; G Egan; M Liotti; S Brannan; D Denton; R Shade; R Robillard; L Madden; B Abplanalp; P T Fox
Journal:  Proc Natl Acad Sci U S A       Date:  2001-02-13       Impact factor: 11.205

6.  Impaired motor coordination and Purkinje cell excitability in mice lacking calretinin.

Authors:  S N Schiffmann; G Cheron; A Lohof; P d'Alcantara; M Meyer; M Parmentier; S Schurmans
Journal:  Proc Natl Acad Sci U S A       Date:  1999-04-27       Impact factor: 11.205

7.  The human red nucleus and lateral cerebellum in supporting roles for sensory information processing.

Authors:  Y Liu; Y Pu; J H Gao; L M Parsons; J Xiong; M Liotti; J M Bower; P T Fo
Journal:  Hum Brain Mapp       Date:  2000-08       Impact factor: 5.038

8.  Sensorimotor mapping of the human cerebellum: fMRI evidence of somatotopic organization.

Authors:  W Grodd; E Hülsmann; M Lotze; D Wildgruber; M Erb
Journal:  Hum Brain Mapp       Date:  2001-06       Impact factor: 5.038

9.  Tactile responses in the granule cell layer of cerebellar folium crus IIa of freely behaving rats.

Authors:  M J Hartmann; J M Bower
Journal:  J Neurosci       Date:  2001-05-15       Impact factor: 6.167

10.  Cerebellar projections to the prefrontal cortex of the primate.

Authors:  F A Middleton; P L Strick
Journal:  J Neurosci       Date:  2001-01-15       Impact factor: 6.167

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