Literature DB >> 8614393

Ifosfamide nephrotoxicity in children: histopathological features in two cases.

B J Morland1, J R Mann, D V Milford, F Raafat, M C Stevens.   

Abstract

We report on two children with rhabdomyosarcoma who received ifosfamide as part of their chemotherapy schedule. Both children subsequently developed severe ifosfamide-induced nephrotoxicity, necessitating electrolyte supplementation. We describe the histopathological findings of renal biopsies performed in these children after the onset of renal dysfunction and comment on the possible mechanisms involved in ifosfamide nephrotoxicity.

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Year:  1996        PMID: 8614393     DOI: 10.1002/(SICI)1096-911X(199607)27:1<57::AID-MPO11>3.0.CO;2-2

Source DB:  PubMed          Journal:  Med Pediatr Oncol        ISSN: 0098-1532


  5 in total

1.  Improvement in karyomegalic interstitial nephritis three years after ifosfamide and cisplatin therapy by corticosteroid.

Authors:  Tomokazu Matsuura; Shu Wakino; Ayumi Yoshifuji; Toshifumi Nakamura; Hirobumi Tokuyama; Akinori Hashiguchi; Konosuke Konishi; Takeshi Iwasa; Masaaki Shoji; Ako Hosono; Ken Ohashi; Hirokazu Chuman; Hiroshi Itoh
Journal:  CEN Case Rep       Date:  2014-06-04

Review 2.  Renal toxicity and chemotherapy in children with cancer.

Authors:  Antonio Ruggiero; Pietro Ferrara; Giorgio Attinà; Daniela Rizzo; Riccardo Riccardi
Journal:  Br J Clin Pharmacol       Date:  2017-09-20       Impact factor: 4.335

3.  Cytochrome P450 3A and 2B6 in the developing kidney: implications for ifosfamide nephrotoxicity.

Authors:  Katarina Aleksa; Doug Matsell; Kris Krausz; Harry Gelboin; Shinya Ito; Gideon Koren
Journal:  Pediatr Nephrol       Date:  2005-05-04       Impact factor: 3.714

4.  Ifosfamide nephrotoxicity in adult patients.

Authors:  Gaël Ensergueix; Nicolas Pallet; Dominique Joly; Charlène Levi; Sophie Chauvet; Claire Trivin; Jean-Francois Augusto; Rémi Boudet; Hail Aboudagga; Guy Touchard; Dominique Nochy; Marie Essig; Eric Thervet; Hélène Lazareth; Alexandre Karras
Journal:  Clin Kidney J       Date:  2019-12-31

5.  Renal failure during chemotherapy: renal biopsy for assessing subacute nephrotoxicity of pemetrexed.

Authors:  Maureen Assayag; Philippe Rouvier; Marion Gauthier; Ghania Costel; Philippe Cluzel; Lucile Mercadal; Gilbert Deray; Corinne Isnard Bagnis
Journal:  BMC Cancer       Date:  2017-11-16       Impact factor: 4.430

  5 in total

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