Literature DB >> 8613979

Tumor necrosis factor-alpha in serum of macaques during SIVmac251 acute infection.

P Clayette1, R Le Grand, O Noack, B Vaslin, R Le Naour, O Benveniste, F Théodoro, P Frétier, D Dormont.   

Abstract

TNF secretion was explored in sera during acute SIV-infection of cynomolgus macaques. A peak of TNF was detected in sera of animals in concomitance with SIV replication. Likewise, AZT treatment delayed and reduced peaks of viral replication and TNF production. Thus, SIVmac251-infected monkey could be an excellent model to explore the interdigitation existing between HIV and TNF in acute and chronic infection and to develop new therapeutic strategies that target the production of this cytokine or its inductive effects.

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Year:  1995        PMID： 8613979     DOI： 10.1111/j.1600-0684.1995.tb00152.x

Source DB:  PubMed          Journal:  J Med Primatol        ISSN： 0047-2565            Impact factor:   0.667


  6 in total

1.  Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS.

Authors:  Christopher Kornfeld; Mickaël J-Y Ploquin; Ivona Pandrea; Abdourahmane Faye; Richard Onanga; Cristian Apetrei; Virginie Poaty-Mavoungou; Pierre Rouquet; Jérôme Estaquier; Lorenzo Mortara; Jean-François Desoutter; Cécile Butor; Roger Le Grand; Pierre Roques; François Simon; Françoise Barré-Sinoussi; Ousmane M Diop; Michaela C Müller-Trutwin
Journal:  J Clin Invest       Date:  2005-03-10       Impact factor: 14.808

2.  Effects of RP 55778, a tumor necrosis factor alpha synthesis inhibitor, on antiviral activity of dideoxynucleosides.

Authors:  P Clayette; N Dereuddre-Bosquet; M Martin; P Fretier; D Dormont
Journal:  Antimicrob Agents Chemother       Date:  1997-04       Impact factor: 5.191

3.  Intestinal intraepithelial lymphocytes are primed for gamma interferon and MIP-1beta expression and display antiviral cytotoxic activity despite severe CD4(+) T-cell depletion in primary simian immunodeficiency virus infection.

Authors:  J J Mattapallil; Z Smit-McBride; M McChesney; S Dandekar
Journal:  J Virol       Date:  1998-08       Impact factor: 5.103

4.  Reduced inflammation and lymphoid tissue immunopathology in rhesus macaques receiving anti-tumor necrosis factor treatment during primary simian immunodeficiency virus infection.

Authors:  Brian Tabb; David R Morcock; Charles M Trubey; Octavio A Quiñones; Xing Pei Hao; Jeremy Smedley; Rhonda Macallister; Michael Piatak; Levelle D Harris; Mirko Paiardini; Guido Silvestri; Jason M Brenchley; W Gregory Alvord; Jeffrey D Lifson; Jacob D Estes
Journal:  J Infect Dis       Date:  2012-10-19       Impact factor: 5.226

5.  Induction of SerpinB2 and Th1/Th2 modulation by SerpinB2 during lentiviral infections in vivo.

Authors:  Lee D Major; Thomas S Partridge; Joy Gardner; Stephen J Kent; Robert de Rose; Andreas Suhrbier; Wayne A Schroder
Journal:  PLoS One       Date:  2013-02-27       Impact factor: 3.240

6.  Tissue-specific B-cell dysfunction and generalized memory B-cell loss during acute SIV infection.

Authors:  Sandrine Peruchon; Nada Chaoul; Chantal Burelout; Benoit Delache; Patricia Brochard; Pascale Laurent; Fabrice Cognasse; Sophie Prévot; Olivier Garraud; Roger Le Grand; Yolande Richard
Journal:  PLoS One       Date:  2009-06-19       Impact factor: 3.240
  6 in total

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