Literature DB >> 861345

Elastogenesis and elastinolytic activity in human breast cancer.

W Hornebeck, J C Derouette, D Brechemier, J J Adnet, L Robert.   

Abstract

Polymeric elastin was isolated and chemically characterized from 34 human breast cancers. There exists a good correlation between the histological and biochemical determinations of elastin; the breast cancer elastin resembles the other elastins isolated from ligamentum nuchae or aorta. Meanwhile it differs by its lower proline content and by its degree of crosslinking as determined by the ratio (Des + IDes/4)Lys. An elastinolytic activity (elastase) was found in human breast cancer extracts. This activity increased with the elastin content of the tumors.

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Year:  1977        PMID： 861345

Source DB:  PubMed          Journal:  Biomedicine        ISSN： 0300-0893


  7 in total

Review 1.  Tumor invasion and host extracellular matrix.

Authors:  B U Pauli; D E Schwartz; E J Thonar; K E Kuettner
Journal:  Cancer Metastasis Rev       Date:  1983       Impact factor: 9.264

2.  Prognostic significance of immunoreactive neutrophil elastase in human breast cancer: long-term follow-up results in 313 patients.

Authors:  Miwa Akizuki; Takashi Fukutomi; Miyuki Takasugi; Satoshi Takahashi; Takashi Sato; Michiko Harao; Takao Mizumoto; Jun-ichi Yamashita
Journal:  Neoplasia       Date:  2007-03       Impact factor: 5.715

3.  Trophoblast- and vascular smooth muscle cell-derived MMP-12 mediates elastolysis during uterine spiral artery remodeling.

Authors:  Lynda K Harris; Samantha D Smith; Rosemary J Keogh; Rebecca L Jones; Philip N Baker; Martin Knöfler; Judith E Cartwright; Guy St J Whitley; John D Aplin
Journal:  Am J Pathol       Date:  2010-08-27       Impact factor: 4.307

4.  Elastin VIII. A correlative study of the aging elastica of arteries and skin.

Authors:  P Pizzolato; R D Lillie
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1978-12-04

5.  Elevated expression of polymorphonuclear leukocyte elastase in breast cancer tissue is associated with tamoxifen failure in patients with advanced disease.

Authors:  J A Foekens; Ch Ries; M P Look; C Gippner-Steppert; J G M Klijn; M Jochum
Journal:  Br J Cancer       Date:  2003-04-07       Impact factor: 7.640

6.  Elafin, an inhibitor of elastase, is a prognostic indicator in breast cancer.

Authors:  Kelly K Hunt; Hannah Wingate; Tomoya Yokota; Yanna Liu; Gordon B Mills; Fan Zhang; Bingliang Fang; Chun-Hui Su; Ming Zhang; Min Yi; Khandan Keyomarsi
Journal:  Breast Cancer Res       Date:  2013-01-15       Impact factor: 6.466

7.  Production of immunoreactive polymorphonuclear leucocyte elastase in human breast cancer cells: possible role of polymorphonuclear leucocyte elastase in the progression of human breast cancer.

Authors:  J I Yamashita; M Ogawa; S Ikei; H Omachi; S I Yamashita; T Saishoji; K Nomura; H Sato
Journal:  Br J Cancer       Date:  1994-01       Impact factor: 7.640
  7 in total

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