| Literature DB >> 8612768 |
S V Seregin1, I N Babkina, A E Nesterov, A N Sinyakov, S N Shchelkunov.
Abstract
To study specific properties of the human gamma-interferon (gamma-IFN) receptor-like proteins of the highly virulent and low virulent strains of variola (smallpox) virus (VAR) recombinant plasmids determining synthesis of these proteins in E. coli cells have been constructed. The recombinant viral gamma-IFN receptor-like proteins have been found to have high interferon-neutralising activity with regard to human gamma-IFN but not murine gamma-IFN and human alpha-IFN. The variola major and variola minor proteins under study do not differ in the efficiency of human gamma-IFN antiviral activity inhibition.Entities:
Mesh:
Substances:
Year: 1996 PMID: 8612768 DOI: 10.1016/0014-5793(96)00069-5
Source DB: PubMed Journal: FEBS Lett ISSN: 0014-5793 Impact factor: 4.124