Literature DB >> 8612762

Increase in activin beta A mRNA in rat hippocampus during long-term potentiation.

K Inokuchi1, A Kato, K Hiraia, F Hishinuma, M Inoue, F Ozawa.   

Abstract

We have used mRNA differential display to isolate genes that are induced by neural activity in rat hippocampus. One of these encodes activin beta A subunit. Convulsive seizure caused by kainate significantly induced the expression of activin beta A mRNA. Furthermore high frequency stimulation (HFS) of perforant pathway, which produced a persistent long-term potentiation (LTP) (>10 h), caused a marked increase at 3 h in the level of activin beta A mRNA at the dentate gyrus of urethane-anesthetized rat. The increase was NMDA receptor-dependent. By contrast the level of inhibin alpha mRNA was not changed following the induction of LTP. THe results suggest a role for activin in maintenance of neural plasticity in the adult brain.

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Year:  1996        PMID： 8612762     DOI： 10.1016/0014-5793(96)00135-4

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  16 in total

1.  A putative transcription factor with seven zinc-finger motifs identified in the developing suprachiasmatic nucleus by the differential display PCR method.

Authors:  Y Maebayashi; Y Shigeyoshi; T Takumi; H Okamura
Journal:  J Neurosci       Date:  1999-11-15       Impact factor: 6.167

2.  Mg(2+) block of Drosophila NMDA receptors is required for long-term memory formation and CREB-dependent gene expression.

Authors:  Tomoyuki Miyashita; Yoshiaki Oda; Junjiro Horiuchi; Jerry C P Yin; Takako Morimoto; Minoru Saitoe
Journal:  Neuron       Date:  2012-06-07       Impact factor: 17.173

3.  Adult Neurogenesis Conserves Hippocampal Memory Capacity.

Authors:  Md Jahangir Alam; Takashi Kitamura; Yoshito Saitoh; Noriaki Ohkawa; Takashi Kondo; Kaoru Inokuchi
Journal:  J Neurosci       Date:  2018-07-09       Impact factor: 6.167

Review 4.  Modulation of the NMDA Receptor Through Secreted Soluble Factors.

Authors:  Waldo Cerpa; Eva Ramos-Fernández; Nibaldo C Inestrosa
Journal:  Mol Neurobiol       Date:  2014-11-29       Impact factor: 5.590

5.  Involvement of the serum response factor coactivator megakaryoblastic leukemia (MKL) in the activin-regulated dendritic complexity of rat cortical neurons.

Authors:  Mitsuru Ishikawa; Naoki Nishijima; Jun Shiota; Hiroyuki Sakagami; Kunihiro Tsuchida; Miho Mizukoshi; Mamoru Fukuchi; Masaaki Tsuda; Akiko Tabuchi
Journal:  J Biol Chem       Date:  2010-08-13       Impact factor: 5.157

6.  Cytokine responses to LTP induction in the rat hippocampus: a comparison of in vitro and in vivo techniques.

Authors:  J L Jankowsky; B E Derrick; P H Patterson
Journal:  Learn Mem       Date:  2000 Nov-Dec       Impact factor: 2.460

7.  LTP induction within a narrow critical period of immature stages enhances the survival of newly generated neurons in the adult rat dentate gyrus.

Authors:  Takashi Kitamura; Yoshito Saitoh; Akiko Murayama; Hiroyuki Sugiyama; Kaoru Inokuchi
Journal:  Mol Brain       Date:  2010-04-28       Impact factor: 4.041

8.  Learning induces the translin/trax RNase complex to express activin receptors for persistent memory.

Authors:  Alan Jung Park; Robbert Havekes; Xiuping Fu; Rolf Hansen; Jennifer C Tudor; Lucia Peixoto; Zhi Li; Yen-Ching Wu; Shane G Poplawski; Jay M Baraban; Ted Abel
Journal:  Elife       Date:  2017-09-20       Impact factor: 8.713

9.  Activin signaling as an emerging target for therapeutic interventions.

Authors:  Kunihiro Tsuchida; Masashi Nakatani; Keisuke Hitachi; Akiyoshi Uezumi; Yoshihide Sunada; Hiroshi Ageta; Kaoru Inokuchi
Journal:  Cell Commun Signal       Date:  2009-06-18       Impact factor: 5.712

10.  Levetiracetam attenuates hippocampal expression of synaptic plasticity-related immediate early and late response genes in amygdala-kindled rats.

Authors:  Kenneth V Christensen; Henrik Leffers; William P Watson; Connie Sánchez; Pekka Kallunki; Jan Egebjerg
Journal:  BMC Neurosci       Date:  2010-01-27       Impact factor: 3.288
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