Literature DB >> 8612070

The catalytic mechanism of cytochrome P450 BM3 involves a 6 A movement of the bound substrate on reduction.

S Modi, M J Sutcliffe, W U Primrose, L Y Lian, G C Roberts.   

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Year:  1996        PMID: 8612070     DOI: 10.1038/nsb0596-414

Source DB:  PubMed          Journal:  Nat Struct Biol        ISSN: 1072-8368


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  22 in total

1.  Roles of key active-site residues in flavocytochrome P450 BM3.

Authors:  M A Noble; C S Miles; S K Chapman; D A Lysek; A C MacKay; G A Reid; R P Hanzlik; A W Munro
Journal:  Biochem J       Date:  1999-04-15       Impact factor: 3.857

Review 2.  Conformational plasticity and structure/function relationships in cytochromes P450.

Authors:  Thomas C Pochapsky; Sophia Kazanis; Marina Dang
Journal:  Antioxid Redox Signal       Date:  2010-10       Impact factor: 8.401

Review 3.  The other kind of biological NMR--studies of enzyme-substrate interactions.

Authors:  G C Roberts
Journal:  Neurochem Res       Date:  1996-09       Impact factor: 3.996

Review 4.  Heme enzyme structure and function.

Authors:  Thomas L Poulos
Journal:  Chem Rev       Date:  2014-01-08       Impact factor: 60.622

5.  An analysis of the role of active site protic residues of cytochrome P-450s: mechanistic and mutational studies on 17alpha-hydroxylase-17,20-lyase (P-45017alpha also CYP17).

Authors:  P Lee-Robichaud; M E Akhtar; M Akhtar
Journal:  Biochem J       Date:  1998-03-01       Impact factor: 3.857

6.  The structural basis for substrate anchoring, active site selectivity, and product formation by P450 PikC from Streptomyces venezuelae.

Authors:  David H Sherman; Shengying Li; Liudmila V Yermalitskaya; Youngchang Kim; Jarrod A Smith; Michael R Waterman; Larissa M Podust
Journal:  J Biol Chem       Date:  2006-07-06       Impact factor: 5.157

7.  Crystal structure of H2O2-dependent cytochrome P450SPalpha with its bound fatty acid substrate: insight into the regioselective hydroxylation of fatty acids at the alpha position.

Authors:  Takashi Fujishiro; Osami Shoji; Shingo Nagano; Hiroshi Sugimoto; Yoshitsugu Shiro; Yoshihito Watanabe
Journal:  J Biol Chem       Date:  2011-06-30       Impact factor: 5.157

8.  Low-frequency variants at the CYP2C9 locus among Puerto Rican patients on warfarin: in silico predictions of functionality and conservation.

Authors:  Karla Claudio-Campos; Mariangeli Moneró-Paredes; Eliud Hernández; Jessicca Renta; Jorge Duconge
Journal:  Pharmacogenomics       Date:  2019-08       Impact factor: 2.533

9.  How does the reductase help to regulate the catalytic cycle of cytochrome P450 3A4 using the conserved water channel?

Authors:  Dan Fishelovitch; Sason Shaik; Haim J Wolfson; Ruth Nussinov
Journal:  J Phys Chem B       Date:  2010-05-06       Impact factor: 2.991

10.  Engineering of a water-soluble plant cytochrome P450, CYP73A1, and NMR-based orientation of natural and alternate substrates in the active site.

Authors:  Guillaume A Schoch; Roger Attias; Maya Belghazi; Patrick M Dansette; Danièle Werck-Reichhart
Journal:  Plant Physiol       Date:  2003-10-23       Impact factor: 8.340

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