Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The effect of dipyridamole on platelet function: correlation with blood levels in man.

Literature DB >> 861128

The effect of dipyridamole on platelet function: correlation with blood levels in man.

S M Rajah, M J Crow, A F Penny, R Ahmad, D A Watson.

Abstract

1 The effect on platelet functions of dipyridamole (a pyrimido-pyrimidine compound) was compared with a control group of patients taking warfarin. 2 Adhesion, aggregation and platelet factor 4 availability showed a significant decrease in the dypyridamole group. 3 Aggregation and platelet factor 4 showed a significant correlation with blood dipyridamole level. 4 Adhesion, aggregation and platelet factor 4 were reduced below the lower limit of normal at blood dipyridamole levels above 3.5 micronmol/1.

Entities: Chemical Species

Mesh：

Substances：

Year: 1977 PMID： 861128 PMCID： PMC1429003 DOI： 10.1111/j.1365-2125.1977.tb00683.x

Source DB: PubMed Journal: Br J Clin Pharmacol ISSN： 0306-5251 Impact factor: 4.335

7 in total

1. Aggregation of blood platelets by adenosine diphosphate and its reversal.

Authors: G V BORN
Journal: Nature Date: 1962-06-09 Impact factor: 49.962

2. Platelet survival in patients with homograft and prosthetic heart valves. Correlation with incidence of thromboembolism.

Authors: S M Manohitharajah; A N Rahman; R J Donnelly; P B Deverall; D A Watson
Journal: Thorax Date: 1974-11 Impact factor: 9.139

3. Platelet and fibrinogen consumption in man.

Authors: L A Harker; S J Slichter
Journal: N Engl J Med Date: 1972-11-16 Impact factor: 91.245

4. The effect on dipyridamole on platelet aggregation and adhesiveness.

Authors: G R Gray; P A Wilson; A S Douglas
Journal: Scott Med J Date: 1968-12 Impact factor: 0.729

Review 5. Rôle of platelets in thrombosis.

Authors: J F Mustard; L Jorgensen; T Hovig; M F Glynn; H C Rowsell
Journal: Thromb Diath Haemorrh Suppl Date: 1966

6. Quantitative estimation of split products of fibrinogen in human serum, relation to diagnosis and treatment.

Authors: C Merskey; G J Kleiner; A J Johnson
Journal: Blood Date: 1966-07 Impact factor: 22.113

7. Effect of a pyrimidopyrimidine derivative on thrombus formation in the rabbit.

Authors: P R Emmons; M J Harrison; A J Honour; J R Mitchell
Journal: Nature Date: 1965-10-16 Impact factor: 49.962

7 in total

11 in total

1. Dipyridamole: pharmacokinetics and effects on aspects of platelet function in man.

Authors: D Gregov; A Jenkins; E Duncan; D Siebert; S Rodgers; B Duncan; F Bochner; J Lloyd
Journal: Br J Clin Pharmacol Date: 1987-10 Impact factor: 4.335

2. Thrombocytosis in rheumatoid arthritis.

Authors: S M Rajah
Journal: Ann Rheum Dis Date: 1978-06 Impact factor: 19.103

3. Anticoagulants and the Björk-Shiley prosthesis.

Authors: S M Rajah; S Rao; D A Watson
Journal: Br Heart J Date: 1979-09

Review 4. Prophylaxis of venous thromboembolism.

Authors: V V Kakkar; M D Stringer
Journal: World J Surg Date: 1990 Sep-Oct Impact factor: 3.352

5. Effects of aspirin and dipyridamole on the degradation of adenosine diphosphate by cultured cells derived from bovine pulmonary artery.

Authors: D J Crutchley; U S Ryan; J W Ryan
Journal: J Clin Invest Date: 1980-07 Impact factor: 14.808

Review 6. Pharmacokinetic optimisation of the treatment of embolic disorders.

Authors: D M Lutomski; M Bottorff; K Sangha
Journal: Clin Pharmacokinet Date: 1995-01 Impact factor: 6.447

7. Dipyridamole treatment in chronic obstructive airways disease: effect on platelet regeneration time.

Authors: E Tremoli; L Bertoli; R Merlini; S Colli; P Maderna; O Mantero; C R Sirtori
Journal: Eur J Clin Pharmacol Date: 1982 Impact factor: 2.953

Review 8. Antiplatelet drugs: clinical pharmacology and therapeutic use.

Authors: A S Gallus
Journal: Drugs Date: 1979-12 Impact factor: 9.546

9. The interaction of varying doses of dipyridamole and acetyl salicylic acid on the inhibition of platelet functions and their effect on bleeding time.

Authors: S M Rajah; A F Penny; M J Crow; M D Pepper; D A Watson
Journal: Br J Clin Pharmacol Date: 1979-11 Impact factor: 4.335

10. Enhanced prostacyclin production by dipyridamole in man.

Authors: G G Neri Serneri; G Masotti; L Poggesi; G Galanti; A Morettini
Journal: Eur J Clin Pharmacol Date: 1981 Impact factor: 2.953