Literature DB >> 8609510

Working memory in medicated patients with Parkinson's disease: the central executive seems to work.

N Fournet1, O Moreaud, J L Roulin, B Naegele, J Pellat.   

Abstract

OBJECTIVE: To determine whether a deficit of the central executive can explain the attentional deficits of patients with Parkinson's disease.
METHODS: Fifteen patients with idiopathic Parkinson's disease and 15 controls were given a dual task paradigm minimising motor demands and combining verbal, visual, or spatial span with two conditions of articulatory suppression.
RESULTS: Although the spans were systematically lower in medicated parkinsonian patients than in controls, suggesting a decrease of central processing resources, there was no direct evidence for a deficit of the central executive.
CONCLUSIONS: A deficit of the central executive either is not an inevitable feature of the disease, or is dependent on the nature of task (visuomotor v cognitive), or is corrected by dopaminergic medication.

Entities:  

Mesh:

Substances:

Year:  1996        PMID: 8609510      PMCID: PMC1073856          DOI: 10.1136/jnnp.60.3.313

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN: 0022-3050            Impact factor:   10.154


  17 in total

1.  Visuospatial working memory in Parkinson's disease.

Authors:  V A Bradley; J L Welch; D J Dick
Journal:  J Neurol Neurosurg Psychiatry       Date:  1989-11       Impact factor: 10.154

2.  Procedural learning and neostriatal dysfunction in man.

Authors:  J A Saint-Cyr; A E Taylor; A E Lang
Journal:  Brain       Date:  1988-08       Impact factor: 13.501

3.  Planning and spatial working memory in Parkinson's disease.

Authors:  R G Morris; J J Downes; B J Sahakian; J L Evenden; A Heald; T W Robbins
Journal:  J Neurol Neurosurg Psychiatry       Date:  1988-06       Impact factor: 10.154

Review 4.  'Subcortical dementia': the neuropsychological evidence.

Authors:  R G Brown; C D Marsden
Journal:  Neuroscience       Date:  1988-05       Impact factor: 3.590

5.  Interference with visualization.

Authors:  W A Phillips; D F Christie
Journal:  Q J Exp Psychol       Date:  1977-11       Impact factor: 2.143

6.  Parkinsonism: onset, progression and mortality.

Authors:  M M Hoehn; M D Yahr
Journal:  Neurology       Date:  1967-05       Impact factor: 9.910

7.  'Frontal' cognitive function in patients with Parkinson's disease 'on' and 'off' levodopa.

Authors:  A M Gotham; R G Brown; C D Marsden
Journal:  Brain       Date:  1988-04       Impact factor: 13.501

8.  Internal versus external cues and the control of attention in Parkinson's disease.

Authors:  R G Brown; C D Marsden
Journal:  Brain       Date:  1988-04       Impact factor: 13.501

9.  A central executive deficit in patients with Parkinson's disease.

Authors:  J C Dalrymple-Alford; A S Kalders; R D Jones; R W Watson
Journal:  J Neurol Neurosurg Psychiatry       Date:  1994-03       Impact factor: 10.154

10.  Neuropsychological evidence for multiple implicit memory systems: a comparison of Alzheimer's, Huntington's, and Parkinson's disease patients.

Authors:  W C Heindel; D P Salmon; C W Shults; P A Walicke; N Butters
Journal:  J Neurosci       Date:  1989-02       Impact factor: 6.167

View more
  8 in total

1.  The selective disruption of spatial working memory by eye movements.

Authors:  Bradley R Postle; Christopher Idzikowski; Sergio Della Sala; Robert H Logie; Alan D Baddeley
Journal:  Q J Exp Psychol (Hove)       Date:  2006-01       Impact factor: 2.143

2.  Cognitive improvement during Tolcapone treatment in Parkinson's disease.

Authors:  M Gasparini; E Fabrizio; V Bonifati; G Meco
Journal:  J Neural Transm (Vienna)       Date:  1997       Impact factor: 3.575

3.  The phonological loop in medicated patients with Parkinson's disease: presence of phonological similarity and word length effects.

Authors:  O Moreaud; N Fournet; J L Roulin; B Naegele; J Pellat
Journal:  J Neurol Neurosurg Psychiatry       Date:  1997-06       Impact factor: 10.154

Review 4.  Inverted-U-shaped dopamine actions on human working memory and cognitive control.

Authors:  Roshan Cools; Mark D'Esposito
Journal:  Biol Psychiatry       Date:  2011-05-04       Impact factor: 13.382

5.  Memory-motor transformations are impaired in Parkinson's disease.

Authors:  Caroline J Ketcham; Timothy L Hodgson; Christopher Kennard; George E Stelmach
Journal:  Exp Brain Res       Date:  2003-01-11       Impact factor: 1.972

6.  Closed head injury and perceptual processing in dual-task situations.

Authors:  G Hein; T Schubert; D Y von Cramon
Journal:  Exp Brain Res       Date:  2004-08-24       Impact factor: 1.972

7.  High-level language production in Parkinson's disease: a review.

Authors:  Lori J P Altmann; Michelle S Troche
Journal:  Parkinsons Dis       Date:  2011-08-05

8.  Cognitive Impairment in Parkinson's Disease: Is It a Unified Phenomenon?

Authors:  Anja Lowit; Peter Howell; Bettina Brendel
Journal:  Brain Impair       Date:  2005       Impact factor: 1.727

  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.