OBJECTIVE: To develop and perform an initial validation of a damage index for systemic lupus erythematosus (SLE). METHODS: A list of items considered to reflect damage in SLE was generated through a nominal group process. A consensus as to which items to be included in an index was reached, together with rules for ascertainment. Each center submitted 2 assessments, 5 years apart, on 2 patients with active and 2 with inactive disease, of whom 1 had increased damage and the other had stable disease. Analysis of variance was used to test the factors physician, time, amount of damage, and activity status. RESULTS: Nineteen physicians completed the damage index on 42 case scenarios. The analysis revealed that the damage index could identify changes in damage seen in patients with both active and inactive disease. Patients who had active disease at both time points had a higher increase in damage. There was good agreement among the physicians on the assessment of damage in these patients. CONCLUSION: This damage index for SLE records damage occurring in patients with SLE regardless of its cause. The index was demonstrated to have content, face, criterion, and discriminant validity.
OBJECTIVE: To develop and perform an initial validation of a damage index for systemic lupus erythematosus (SLE). METHODS: A list of items considered to reflect damage in SLE was generated through a nominal group process. A consensus as to which items to be included in an index was reached, together with rules for ascertainment. Each center submitted 2 assessments, 5 years apart, on 2 patients with active and 2 with inactive disease, of whom 1 had increased damage and the other had stable disease. Analysis of variance was used to test the factors physician, time, amount of damage, and activity status. RESULTS: Nineteen physicians completed the damage index on 42 case scenarios. The analysis revealed that the damage index could identify changes in damage seen in patients with both active and inactive disease. Patients who had active disease at both time points had a higher increase in damage. There was good agreement among the physicians on the assessment of damage in these patients. CONCLUSION: This damage index for SLE records damage occurring in patients with SLE regardless of its cause. The index was demonstrated to have content, face, criterion, and discriminant validity.
Authors: M B Urowitz; D Gladman; D Ibañez; S C Bae; J Sanchez-Guerrero; C Gordon; A Clarke; S Bernatsky; P R Fortin; J G Hanly; D J Wallace; D Isenberg; A Rahman; G S Alarcón; J T Merrill; E Ginzler; M Khamashta; O Nived; G Sturfelt; I N Bruce; K Steinsson; S Manzi; R Ramsey-Goldman; M A Dooley; A Zoma; K Kalunian; M Ramos; R F Van Vollenhoven; C Aranow; T Stoll; M Petri; P Maddison Journal: Arthritis Care Res (Hoboken) Date: 2010-06 Impact factor: 4.794
Authors: R Lertnawapan; A Bian; Y H Rho; P Raggi; A Oeser; J F Solus; T Gebretsadik; A Shintani; C M Stein Journal: Lupus Date: 2011-11-09 Impact factor: 2.911
Authors: Carly Skamra; Juanita Romero-Diaz; Alexander Sandhu; QiQuan Huang; Jungwha Lee; William Pearce; David D McPherson; Kim Sutton-Tyrrell; Richard Pope; Rosalind Ramsey-Goldman Journal: Rheumatology (Oxford) Date: 2013-02-04 Impact factor: 7.580
Authors: Lina Wirestam; Helena Enocsson; Thomas Skogh; Leonid Padyukov; Andreas Jönsen; Murray B Urowitz; Dafna D Gladman; Juanita Romero-Diaz; Sang-Cheol Bae; Paul R Fortin; Jorge Sanchez-Guerrero; Ann E Clarke; Sasha Bernatsky; Caroline Gordon; John G Hanly; Daniel Wallace; David A Isenberg; Anisur Rahman; Joan Merrill; Ellen Ginzler; Graciela S Alarcón; W Winn Chatham; Michelle Petri; Munther Khamashta; Cynthia Aranow; Meggan Mackay; Mary Anne Dooley; Susan Manzi; Rosalind Ramsey-Goldman; Ola Nived; Kristjan Steinsson; Asad Zoma; Guillermo Ruiz-Irastorza; Sam Lim; Ken Kalunian; Murat Inanc; Ronald van Vollenhoven; Manuel Ramos-Casals; Diane L Kamen; Søren Jacobsen; Christine Peschken; Anca Askanase; Thomas Stoll; Ian N Bruce; Jonas Wetterö; Christopher Sjöwall Journal: J Rheumatol Date: 2019-01-15 Impact factor: 4.666