| Literature DB >> 8606163 |
A V Franco1, D Liu, P R Reeves.
Abstract
The modal distribution of O-antigen chain length is determined by the Wzz (Cld/Rol) protein in those cases in which it has been studied. The system of O-antigen synthesis in Escherichia coli serotypes O8 and O9 is different from that reported for most other bacteria, and chain length distribution is thought not to be determined by a Wzz protein. We report the existence in E. coli O8 and O9 strains of wzz genes which are very similar to and have sequences within the range of variation of those which determine the chain length of typical O antigens. We also find that wzz genes previously identified by their effect on O-antigen chain length, when cloned and transferred to O8 and O9 strains, affect the chain length of a capsule-related form of LPS, K(LPS). We conclude that in at least some O8 and O9 strains there is a wzz gene which controls the chain length of K(LPS) but has no effect on the O8 or O9 antigen.Entities:
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Year: 1996 PMID： 8606163 PMCID： PMC177884 DOI： 10.1128/jb.178.7.1903-1907.1996
Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490