| Literature DB >> 8605246 |
K Miyamoto1, T Shiraga, K Morita, H Yamamoto, H Haga, Y Taketani, I Tamai, Y Sai, A Tsuji, E Takeda.
Abstract
Complementary DNA clones encoding the rat PepT1 small-intestinal oligopeptide transporter were isolated from a jejunal library by cross-hybridization with a rabbit PepT1 cDNA probe. The cDNA sequence indicates that rat PepT1 is composed of 710 amino acids and shows 77% and 83% amino acid sequence identity with rabbit and human PepT1, respectively. Northern blot analysis detected rat PepT1 mRNA in the small intestine and kidney. Intestinal PepT1 mRNA levels were highest in 4-day old rats, and then decreased reaching the adult level by day 28 after birth. These results indicate that the expressions of PepT1 gene change markedly during development.Entities:
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Year: 1996 PMID： 8605246 DOI： 10.1016/0167-4781(95)00208-1
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002