Literature DB >> 8602760

Use of anti-neurofilament antibody to identify paired-helical filaments in inclusion-body myositis.

V Askanas1, R B Alvarez, M Mirabella, W K Engel.   

Abstract

Paired-helical filaments (PHFs) are an important diagnostic criterion of the inclusion-body myositis (IBM) muscle biopsy; but, until now, their presence could be identified only by electronmicroscopy. In this report, we describe an easy immunocytochemical procedure, utilizing commercially available antibody, that enables reliable identification of muscle PHFs by light microscopy. This procedure greatly facilitates diagnosis of IBM.

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Year:  1996        PMID： 8602760     DOI： 10.1002/ana.410390318

Source DB:  PubMed          Journal:  Ann Neurol        ISSN： 0364-5134            Impact factor:   10.422


  10 in total

1.  Paired helical filaments of inclusion-body myositis muscle contain RNA and survival motor neuron protein.

Authors:  A Broccolini; W K Engel; R B Alvarez; V Askanas
Journal:  Am J Pathol       Date:  2000-04       Impact factor: 4.307

2.  ANT1 is reduced in sporadic inclusion body myositis.

Authors:  E Barca; M Aguennouz; A Mazzeo; S Messina; A Toscano; G L Vita; S Portaro; D Parisi; C Rodolico
Journal:  Neurol Sci       Date:  2012-02-21       Impact factor: 3.307

3.  Proteasome inhibition and aggresome formation in sporadic inclusion-body myositis and in amyloid-beta precursor protein-overexpressing cultured human muscle fibers.

Authors:  Pietro Fratta; W King Engel; Janis McFerrin; Kelvin J A Davies; Sharon W Lin; Valerie Askanas
Journal:  Am J Pathol       Date:  2005-08       Impact factor: 4.307

4.  Light and electron microscopic immunolocalization of presenilin 1 in abnormal muscle fibers of patients with sporadic inclusion-body myositis and autosomal-recessive inclusion-body myopathy.

Authors:  V Askanas; W K Engel; C C Yang; R B Alvarez; V M Lee; T Wisniewski
Journal:  Am J Pathol       Date:  1998-04       Impact factor: 4.307

Review 5.  Inclusion-body myositis: muscle-fiber molecular pathology and possible pathogenic significance of its similarity to Alzheimer's and Parkinson's disease brains.

Authors:  Valerie Askanas; W King Engel
Journal:  Acta Neuropathol       Date:  2008-10-31       Impact factor: 17.088

Review 6.  Newest pathogenetic considerations in inclusion-body myositis: possible role of amyloid-beta, cholesterol, relation to aging and to Alzheimer's disease.

Authors:  Valerie Askanas; W King Engel
Journal:  Curr Rheumatol Rep       Date:  2002-10       Impact factor: 4.592

7.  Endoplasmic reticulum stress and unfolded protein response in inclusion body myositis muscle.

Authors:  Gaetano Vattemi; W King Engel; Janis McFerrin; Valerie Askanas
Journal:  Am J Pathol       Date:  2004-01       Impact factor: 4.307

8.  Comparative utility of LC3, p62 and TDP-43 immunohistochemistry in differentiation of inclusion body myositis from polymyositis and related inflammatory myopathies.

Authors:  Annie Hiniker; Brianne H Daniels; Han S Lee; Marta Margeta
Journal:  Acta Neuropathol Commun       Date:  2013-07-01       Impact factor: 7.801

9.  Anti-cN1A Antibodies Are Associated with More Severe Dysphagia in Sporadic Inclusion Body Myositis.

Authors:  Matteo Lucchini; Lorenzo Maggi; Elena Pegoraro; Massimiliano Filosto; Carmelo Rodolico; Giovanni Antonini; Matteo Garibaldi; Maria Lucia Valentino; Gabriele Siciliano; Giorgio Tasca; Valeria De Arcangelis; Chiara De Fino; Massimiliano Mirabella
Journal:  Cells       Date:  2021-05-10       Impact factor: 6.600

10.  Endoplasmic Reticulum Stress Induces Myostatin High Molecular Weight Aggregates and Impairs Mature Myostatin Secretion.

Authors:  Rishibha Sachdev; Karin Kappes-Horn; Lydia Paulsen; Yvonne Duernberger; Catharina Pleschka; Philip Denner; Bishwajit Kundu; Jens Reimann; Ina Vorberg
Journal:  Mol Neurobiol       Date:  2018-03-15       Impact factor: 5.590
  10 in total

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