Literature DB >> 8600372

No increase in micronuclei frequency in cultured blood lymphocytes from a group of filling station attendants.

M Pitarque1, E Carbonell, N Lapeña, M Marsá, M Torres, A Creus, N Xamena, R Marcos.   

Abstract

Service station attendants are workers that are definitely exposed to petroleum derivatives. Taking into account that this exposure has been considered to possess genotoxic risk, here we present data on the biomonitoring of a group of 50 service station workers and 43 controls. Micronuclei (MN) from peripheral blood lymphocytes has been considered as the genetic endpoint to be studied and, in addition, data on the concentration of aromatic hydrocarbons at the workplace, urinary metabolites and differential white blood cell count have also been analysed. The results obtained indicate no significant differences between petrol station attendants and controls, when the effects of petrol exposure were investigated by differential white blood cell count and analysis of MN frequencies in phytohaemagglutinin-stimulated lymphocytes. Regarding the urinary metabolites, a significant increase in the phenol level was found in the exposed workers.

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Year:  1996        PMID: 8600372     DOI: 10.1016/0165-1218(95)00091-7

Source DB:  PubMed          Journal:  Mutat Res        ISSN: 0027-5107            Impact factor:   2.433


  6 in total

1.  Association between urinary 1-hydroxypyrene and genotoxic effects in coke oven workers.

Authors:  E Siwińska; D Mielzyńska; L Kapka
Journal:  Occup Environ Med       Date:  2004-03       Impact factor: 4.402

Review 2.  Epigenetic Effects of Benzene in Hematologic Neoplasms: The Altered Gene Expression.

Authors:  Giovanna Spatari; Alessandro Allegra; Mariella Carrieri; Giovanni Pioggia; Sebastiano Gangemi
Journal:  Cancers (Basel)       Date:  2021-05-14       Impact factor: 6.639

3.  Health risk assessment of ambient air concentrations of benzene, toluene and xylene (BTX) in service station environments.

Authors:  Benjamin Edokpolo; Qiming Jimmy Yu; Des Connell
Journal:  Int J Environ Res Public Health       Date:  2014-06-18       Impact factor: 3.390

4.  Health risk characterization for exposure to benzene in service stations and petroleum refineries environments using human adverse response data.

Authors:  Benjamin Edokpolo; Qiming Jimmy Yu; Des Connell
Journal:  Toxicol Rep       Date:  2015-06-05

5.  Evaluation of Micronucleus in Exfoliated Buccal Epithelial Cells Using Liquid-based Cytology Preparation in Petrol Station Workers.

Authors:  P Arul; Smitha Shetty; Suresh Masilamani; C Akshatha; B J Naveen Kumar
Journal:  Indian J Med Paediatr Oncol       Date:  2017 Jul-Sep

6.  A Quantitative Meta-Analysis of the Relation between Occupational Benzene Exposure and Biomarkers of Cytogenetic Damage.

Authors:  Bernice Scholten; Jelle Vlaanderen; Rob Stierum; Lützen Portengen; Nat Rothman; Qing Lan; Anjoeka Pronk; Roel Vermeulen
Journal:  Environ Health Perspect       Date:  2020-08-12       Impact factor: 9.031

  6 in total

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