Literature DB >> 8599623

[Ascorbic acid in the plasma and blood cells of women with breast cancer. The effect of the consumption of food with an elevated content of this vitamin].

C Núñez Martín1, A Ortiz de Apodaca y Ruiz.   

Abstract

The levels of ascorbic acid in plasma and in blood cells (erythrocytes, neutrophils, and platelets) was studied in a group of 30 women with recent onset of breast cancer, and they were compared with a group of 30 healthy women, thus establishing the possible correlations between them. At the same time, these levels were related to the frequency of consumption of foods with a high content of this vitamin (fruits, potatoes, and vegetables). The women with breast cancer present plasma levels of ascorbic acid which are significantly lower (p < 0.01), and platelet levels which are significantly higher (p < 0.05). There are no differences with respect to the levels in erythrocytes or neutrophils. The frequency of consumption of vegetables, which is higher in the controls (p < 0.001), is significantly related to higher levels of ascorbic acid in plasma (r = 0.458), and erythrocytes (r = 0.444) in this group, but we did not find any correlation in the group of the patients. The frequency of fruit or potatoes consumption, which is very similar in both groups, does not appear to lead to significant differences in the ascorbic acid contents.

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Year:  1995        PMID: 8599623

Source DB:  PubMed          Journal:  Nutr Hosp        ISSN: 0212-1611            Impact factor:   1.057


  19 in total

1.  In vitro and in vivo antitumorigenic activity of a mixture of lysine, proline, ascorbic acid, and green tea extract on human breast cancer lines MDA-MB-231 and MCF-7.

Authors:  M Waheed Roomi; Vadim Ivanov; Tatiana Kalinovsky; Aleksandra Niedzwiecki; Matthias Rath
Journal:  Med Oncol       Date:  2005       Impact factor: 3.064

2.  In vivo and in vitro antitumor effect of ascorbic acid, lysine, proline, arginine, and green tea extract on human fibrosarcoma cells HT-1080.

Authors:  M Waheed Roomi; Vadim Ivanov; Tatiana Kalinovsky; Aleksandra Niedzwiecki; Matthias Rath
Journal:  Med Oncol       Date:  2006       Impact factor: 3.064

3.  Effect of a nutrient mixture on the localization of extracellular matrix proteins in HeLa human cervical cancer xenografts in female nude mice.

Authors:  M Waheed Roomi; John Cha; Tatiana Kalinovsky; Nusrath Roomi; Aleksandra Niedzwiecki; Matthias Rath
Journal:  Exp Ther Med       Date:  2015-06-23       Impact factor: 2.447

4.  Antitumor effect of a combination of lysine, proline, arginine, ascorbic acid, and green tea extract on pancreatic cancer cell line MIA PaCa-2.

Authors:  M Waheed Roomi; Vadim Ivanov; Tatiana Kalinovsky; Aleksandra Niedzwiecki; Matthias Rath
Journal:  Int J Gastrointest Cancer       Date:  2005

Review 5.  Micronutrient synergy--a new tool in effective control of metastasis and other key mechanisms of cancer.

Authors:  A Niedzwiecki; M W Roomi; T Kalinovsky; M Rath
Journal:  Cancer Metastasis Rev       Date:  2010-09       Impact factor: 9.264

6.  Inhibition of cell invasion and MMP production by a nutrient mixture in malignant liposarcoma cell line SW-872.

Authors:  M W Roomi; V Ivanov; T Kalinovsky; Aleksandra Niedzwiecki; M Rath
Journal:  Med Oncol       Date:  2007       Impact factor: 3.064

7.  Ascorbate supplementation inhibits growth and metastasis of B16FO melanoma and 4T1 breast cancer cells in vitamin C-deficient mice.

Authors:  John Cha; M Waheed Roomi; Vadim Ivanov; Tatiana Kalinovsky; Aleksandra Niedzwiecki; Matthias Rath
Journal:  Int J Oncol       Date:  2012-11-21       Impact factor: 5.650

8.  In vitro and in vivo inhibition of human Fanconi anemia-associated head and neck squamous cell carcinoma by a novel nutrient mixture.

Authors:  M W Roomi; T Kalinovsky; N W Roomi; A Niedzwiecki; M Rath
Journal:  Int J Oncol       Date:  2012-09-24       Impact factor: 5.650

9.  Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in human lung cancer and mesothelioma cell lines.

Authors:  M Waheed Roomi; Tatiana Kalinovsky; Aleksandra Niedzwiecki; Matthias Rath
Journal:  Int J Oncol       Date:  2013-04-03       Impact factor: 5.650

10.  Inhibition of the SK-N-MC human neuroblastoma cell line in vivo and in vitro by a novel nutrient mixture.

Authors:  M Waheed Roomi; Tatiana Kalinovsky; Nusrath W Roomi; Aleksandra Niedzwiecki; Matthias Rath
Journal:  Oncol Rep       Date:  2013-02-27       Impact factor: 3.906

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