Literature DB >> 8595200

Expression of melanocortin 1 receptor in periaqueductal gray matter.

Y Xia1, J E Wikberg, V Chhajlani.   

Abstract

The localization of the melanocortin 1 (MC1) receptor in brain was investigated by in situ hybridization and immunohistochemistry. In rat periaqueductal gray matter (PAG), a small number of cells which displayed a punctate distribution showed a specific hybridization signal for MC1 receptor mRNA, whereas other regions studied were negative. In human PAG, the immunoreactivity for MC1 receptor was detected in scattered cells. These results indicate that a restricted distribution of MC1 receptor is present in the central nervous system.

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Year:  1995        PMID： 8595200     DOI： 10.1097/00001756-199511000-00022

Source DB:  PubMed          Journal:  Neuroreport        ISSN： 0959-4965            Impact factor:   1.837


  31 in total

1.  MC(1) receptors are constitutively expressed on leucocyte subpopulations with antigen presenting and cytotoxic functions.

Authors:  G Neumann Andersen; O Nagaeva; I Mandrika; R Petrovska; R Muceniece; L Mincheva-Nilsson; J E Wikberg
Journal:  Clin Exp Immunol       Date:  2001-12       Impact factor: 4.330

2.  Approaches to the rational design of selective melanocortin receptor antagonists.

Authors:  Victor J Hruby; Minying Cai; Joel Nyberg; Dhanasekaran Muthu
Journal:  Expert Opin Drug Discov       Date:  2011-03-24       Impact factor: 6.098

3.  The protective effects of the melanocortin receptor (MCR) agonist, melanotan-II (MTII), against binge-like ethanol drinking are facilitated by deletion of the MC3 receptor in mice.

Authors:  J J Olney; G M Sprow; M Navarro; T E Thiele
Journal:  Neuropeptides       Date:  2013-11-15       Impact factor: 3.286

4.  alpha-MSH modulates local and circulating tumor necrosis factor-alpha in experimental brain inflammation.

Authors:  N Rajora; G Boccoli; D Burns; S Sharma; A P Catania; J M Lipton
Journal:  J Neurosci       Date:  1997-03-15       Impact factor: 6.167

5.  The melanoma-linked "redhead" MC1R influences dopaminergic neuron survival.

Authors:  Xiqun Chen; Hongxiang Chen; Waijiao Cai; Michael Maguire; Bailiu Ya; Fuxing Zuo; Robert Logan; Hui Li; Katey Robinson; Charles R Vanderburg; Yang Yu; Yinsheng Wang; David E Fisher; Michael A Schwarzschild
Journal:  Ann Neurol       Date:  2017-01-23       Impact factor: 10.422

6.  An unusual conformation of γ-melanocyte-stimulating hormone analogues leads to a selective human melanocortin 1 receptor antagonist for targeting melanoma cells.

Authors:  Minying Cai; Magda Stankova; Dhanasekaran Muthu; Alexander Mayorov; Zhehui Yang; Devendra Trivedi; Christopher Cabello; Victor J Hruby
Journal:  Biochemistry       Date:  2013-01-15       Impact factor: 3.162

7.  A novel selective melanocortin-4 receptor agonist reduces food intake in rats and mice without producing aversive consequences.

Authors:  S C Benoit; M W Schwartz; J L Lachey; M M Hagan; P A Rushing; K A Blake; K A Yagaloff; G Kurylko; L Franco; W Danhoo; R J Seeley
Journal:  J Neurosci       Date:  2000-05-01       Impact factor: 6.167

Review 8.  Synaptic changes induced by melanocortin signalling.

Authors:  Vanni Caruso; Malin C Lagerström; Pawel K Olszewski; Robert Fredriksson; Helgi B Schiöth
Journal:  Nat Rev Neurosci       Date:  2014-02       Impact factor: 34.870

9.  Involvement of the melanocortin-1 receptor in acute pain and pain of inflammatory but not neuropathic origin.

Authors:  Ada Delaney; Margaret Keighren; Susan M Fleetwood-Walker; Ian J Jackson
Journal:  PLoS One       Date:  2010-09-13       Impact factor: 3.240

10.  Prolylcarboxypeptidase (PRCP) as a new target for obesity treatment.

Authors:  B Shariat-Madar; D Kolte; A Verlangieri; Z Shariat-Madar
Journal:  Diabetes Metab Syndr Obes       Date:  2010-04       Impact factor: 3.168
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